node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG31342 | Tmtc3 | FBpp0112315 | FBpp0071561 | FI13065p. | Protein O-mannosyl-transferase Tmtc3; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. | 0.594 |
CG9986 | Tmtc3 | FBpp0084673 | FBpp0071561 | LD27564p. | Protein O-mannosyl-transferase Tmtc3; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. | 0.584 |
IntS1 | RpII140 | FBpp0072077 | FBpp0310926 | Integrator complex subunit 1; Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box- dependent processing. Involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5. Required for the normal expression of the Integrator complex component IntS12. May mediate recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (By similarity). | DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is [...] | 0.985 |
IntS1 | Tmtc3 | FBpp0072077 | FBpp0071561 | Integrator complex subunit 1; Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box- dependent processing. Involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5. Required for the normal expression of the Integrator complex component IntS12. May mediate recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (By similarity). | Protein O-mannosyl-transferase Tmtc3; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. | 0.586 |
IntS1 | asun | FBpp0072077 | FBpp0082713 | Integrator complex subunit 1; Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box- dependent processing. Involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5. Required for the normal expression of the Integrator complex component IntS12. May mediate recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (By similarity). | Protein asunder; Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box- dependent processing. Involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1 and U5. Plays a role as a regulator of spermatogenesis. Crucial regulator of the mitotic cell cycle and development. Required for the correct dynein-dynactin perinuclear localization important for nucleus- centrosome coupling that occur upon meiotic progression of primary spermatocytes. Plays a role in sperm motility and fertility. May hav [...] | 0.999 |
NANS | Tmtc3 | FBpp0082060 | FBpp0071561 | Sialic acid synthase; Produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy- D-glycero-D-galacto-nononic acid (KDN). Can also use N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively. Essential for biosynthesis of sialic acids in neurons of the central nervous system. | Protein O-mannosyl-transferase Tmtc3; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. | 0.619 |
PIG-B | PIG-Z | FBpp0073008 | FBpp0310802 | GPI mannosyltransferase 3; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2- GlcN-acyl-PI during GPI precursor assembly (By similarity). Belongs to the glycosyltransferase 22 family. PIGB subfamily. | GPI mannosyltransferase 4; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers a fourth mannose to some trimannosyl- GPIs during GPI precursor assembly (By similarity). | 0.781 |
PIG-B | Tmtc3 | FBpp0073008 | FBpp0071561 | GPI mannosyltransferase 3; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2- GlcN-acyl-PI during GPI precursor assembly (By similarity). Belongs to the glycosyltransferase 22 family. PIGB subfamily. | Protein O-mannosyl-transferase Tmtc3; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. | 0.691 |
PIG-B | tw | FBpp0073008 | FBpp0307386 | GPI mannosyltransferase 3; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2- GlcN-acyl-PI during GPI precursor assembly (By similarity). Belongs to the glycosyltransferase 22 family. PIGB subfamily. | Protein O-mannosyl-transferase 2; Twisted (tw) encodes a protein that transfers a mannose to the Ser/Thr residues of dystroglycan, via forming an heterodimer with the product of rt. Its roles include myogenesis, muscle architecture and cell adhesion. | 0.419 |
PIG-Z | PIG-B | FBpp0310802 | FBpp0073008 | GPI mannosyltransferase 4; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers a fourth mannose to some trimannosyl- GPIs during GPI precursor assembly (By similarity). | GPI mannosyltransferase 3; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2- GlcN-acyl-PI during GPI precursor assembly (By similarity). Belongs to the glycosyltransferase 22 family. PIGB subfamily. | 0.781 |
PIG-Z | Tmtc3 | FBpp0310802 | FBpp0071561 | GPI mannosyltransferase 4; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers a fourth mannose to some trimannosyl- GPIs during GPI precursor assembly (By similarity). | Protein O-mannosyl-transferase Tmtc3; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. | 0.613 |
PIG-Z | rt | FBpp0310802 | FBpp0075877 | GPI mannosyltransferase 4; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers a fourth mannose to some trimannosyl- GPIs during GPI precursor assembly (By similarity). | Protein O-mannosyltransferase 1; Rotated abdomen (rt) encodes a protein that transfers a mannose to the Ser/Thr residues of the product of Dg, via forming an heterodimer with the product of tw. Its roles include myogenesis, muscle architecture and cell adhesion. | 0.459 |
PIG-Z | tw | FBpp0310802 | FBpp0307386 | GPI mannosyltransferase 4; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers a fourth mannose to some trimannosyl- GPIs during GPI precursor assembly (By similarity). | Protein O-mannosyl-transferase 2; Twisted (tw) encodes a protein that transfers a mannose to the Ser/Thr residues of dystroglycan, via forming an heterodimer with the product of rt. Its roles include myogenesis, muscle architecture and cell adhesion. | 0.512 |
RpII140 | IntS1 | FBpp0310926 | FBpp0072077 | DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is [...] | Integrator complex subunit 1; Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box- dependent processing. Involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5. Required for the normal expression of the Integrator complex component IntS12. May mediate recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (By similarity). | 0.985 |
RpII140 | Tmtc3 | FBpp0310926 | FBpp0071561 | DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is [...] | Protein O-mannosyl-transferase Tmtc3; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. | 0.590 |
RpII140 | asun | FBpp0310926 | FBpp0082713 | DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is [...] | Protein asunder; Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box- dependent processing. Involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1 and U5. Plays a role as a regulator of spermatogenesis. Crucial regulator of the mitotic cell cycle and development. Required for the correct dynein-dynactin perinuclear localization important for nucleus- centrosome coupling that occur upon meiotic progression of primary spermatocytes. Plays a role in sperm motility and fertility. May hav [...] | 0.510 |
Tmtc3 | CG31342 | FBpp0071561 | FBpp0112315 | Protein O-mannosyl-transferase Tmtc3; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. | FI13065p. | 0.594 |
Tmtc3 | CG9986 | FBpp0071561 | FBpp0084673 | Protein O-mannosyl-transferase Tmtc3; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. | LD27564p. | 0.584 |
Tmtc3 | IntS1 | FBpp0071561 | FBpp0072077 | Protein O-mannosyl-transferase Tmtc3; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. | Integrator complex subunit 1; Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box- dependent processing. Involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5. Required for the normal expression of the Integrator complex component IntS12. May mediate recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (By similarity). | 0.586 |
Tmtc3 | NANS | FBpp0071561 | FBpp0082060 | Protein O-mannosyl-transferase Tmtc3; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. | Sialic acid synthase; Produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy- D-glycero-D-galacto-nononic acid (KDN). Can also use N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively. Essential for biosynthesis of sialic acids in neurons of the central nervous system. | 0.619 |