| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATbp | dve | FBpp0291188 | FBpp0071689 | AT-rich binding protein; May be a transcription factor for genes having (A+T) stretches in their promoter and/or enhancer regions. Binds to AT rich DNA. | Defective proventriculus (dve) encodes a transcriptional repressor that binds to the K50 site. It is involved in developmental patterning, cell-type specification, and functional differentiation. | 0.843 |
| CTCF | dve | FBpp0076588 | FBpp0071689 | GH14774p; CTCF (CTCF) encodes a ubiquitous transcription factor that binds to insulators and domain boundaries. It mediates insulator function and blocks enhancers by binding to the product of Cp190. It contributes to long-range chromatin interaction, organizes chromatin domain boundaries and coordinates nuclear architecture. | Defective proventriculus (dve) encodes a transcriptional repressor that binds to the K50 site. It is involved in developmental patterning, cell-type specification, and functional differentiation. | 0.614 |
| ClpP | dve | FBpp0304498 | FBpp0071689 | ATP-dependent Clp protease proteolytic subunit; ATP-dependent peptidase activity; ATPase binding; serine-type endopeptidase activity. It is involved in the biological process described with: protein quality control for misfolded or incompletely synthesized proteins; proteolysis involved in cellular protein catabolic process; regulation of mitochondrial gene expression. | Defective proventriculus (dve) encodes a transcriptional repressor that binds to the K50 site. It is involved in developmental patterning, cell-type specification, and functional differentiation. | 0.726 |
| ClpP | ubl | FBpp0304498 | FBpp0085529 | ATP-dependent Clp protease proteolytic subunit; ATP-dependent peptidase activity; ATPase binding; serine-type endopeptidase activity. It is involved in the biological process described with: protein quality control for misfolded or incompletely synthesized proteins; proteolysis involved in cellular protein catabolic process; regulation of mitochondrial gene expression. | Ubiquitin-like protein 5; Protein tag. It is involved in the biological process described with: mRNA splicing, via spliceosome; cellular protein modification process. | 0.663 |
| Pph13 | Rh3 | FBpp0077730 | FBpp0083284 | PvuII-PstI homology 13 (Pph13) encodes a paired-class homeodomain protein. It is critical for rhabdomeric photoreceptor differentiation, phototransduction and rhabdomere morphogenesis. | Rhodopsin 3 (Rh3) encodes a Rhodopsin GPCR protein that responds to UV light and activates the phototransduction cascade that leads to photoreceptor depolarization. Rh3 is expressed in R7 photoreceptors in a stochastic manner: 35% of R7 photoreceptors express Rh3 while the remaining 65% express another UV-sensitive Rhodopsin encoded by Rh4. | 0.810 |
| Pph13 | Rh4 | FBpp0077730 | FBpp0075097 | PvuII-PstI homology 13 (Pph13) encodes a paired-class homeodomain protein. It is critical for rhabdomeric photoreceptor differentiation, phototransduction and rhabdomere morphogenesis. | Opsin Rh4; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. | 0.689 |
| Pph13 | Rh5 | FBpp0077730 | FBpp0309539 | PvuII-PstI homology 13 (Pph13) encodes a paired-class homeodomain protein. It is critical for rhabdomeric photoreceptor differentiation, phototransduction and rhabdomere morphogenesis. | Rhodopsin 5 (Rh5) encodes a visual GPCR opsin that covalently binds the chromophore retinal. A photon of light stimulates the isomerization of retinal resulting in a conformational change in the product of Rh5 and signal activation. Its peak sensitivity is in the blue and it is expressed in a subclass of R8 photoreceptors; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. | 0.849 |
| Pph13 | Rh6 | FBpp0077730 | FBpp0312616 | PvuII-PstI homology 13 (Pph13) encodes a paired-class homeodomain protein. It is critical for rhabdomeric photoreceptor differentiation, phototransduction and rhabdomere morphogenesis. | Opsin Rh6; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. | 0.852 |
| Pph13 | dve | FBpp0077730 | FBpp0071689 | PvuII-PstI homology 13 (Pph13) encodes a paired-class homeodomain protein. It is critical for rhabdomeric photoreceptor differentiation, phototransduction and rhabdomere morphogenesis. | Defective proventriculus (dve) encodes a transcriptional repressor that binds to the K50 site. It is involved in developmental patterning, cell-type specification, and functional differentiation. | 0.682 |
| Pph13 | oc | FBpp0077730 | FBpp0423136 | PvuII-PstI homology 13 (Pph13) encodes a paired-class homeodomain protein. It is critical for rhabdomeric photoreceptor differentiation, phototransduction and rhabdomere morphogenesis. | Homeotic protein ocelliless; Transcriptional regulator involved in pattern formation and cell determination in the embryonic CNS and larval imaginal disks. Also later in development to coordinate the expression of regulatory and structural genes required for photoreceptor cell fate in the ocelli. Has a dual role in the terminal differentiation of subtypes of photoreceptors by regulating rhodopsin (rh) expression: essential for establishing the expression of rh genes in the pale subset of ommatidia as well as repressing Rh6 in outer photoreceptors. Belongs to the paired homeobox family. | 0.520 |
| Rh3 | Pph13 | FBpp0083284 | FBpp0077730 | Rhodopsin 3 (Rh3) encodes a Rhodopsin GPCR protein that responds to UV light and activates the phototransduction cascade that leads to photoreceptor depolarization. Rh3 is expressed in R7 photoreceptors in a stochastic manner: 35% of R7 photoreceptors express Rh3 while the remaining 65% express another UV-sensitive Rhodopsin encoded by Rh4. | PvuII-PstI homology 13 (Pph13) encodes a paired-class homeodomain protein. It is critical for rhabdomeric photoreceptor differentiation, phototransduction and rhabdomere morphogenesis. | 0.810 |
| Rh3 | Rh4 | FBpp0083284 | FBpp0075097 | Rhodopsin 3 (Rh3) encodes a Rhodopsin GPCR protein that responds to UV light and activates the phototransduction cascade that leads to photoreceptor depolarization. Rh3 is expressed in R7 photoreceptors in a stochastic manner: 35% of R7 photoreceptors express Rh3 while the remaining 65% express another UV-sensitive Rhodopsin encoded by Rh4. | Opsin Rh4; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. | 0.845 |
| Rh3 | Rh5 | FBpp0083284 | FBpp0309539 | Rhodopsin 3 (Rh3) encodes a Rhodopsin GPCR protein that responds to UV light and activates the phototransduction cascade that leads to photoreceptor depolarization. Rh3 is expressed in R7 photoreceptors in a stochastic manner: 35% of R7 photoreceptors express Rh3 while the remaining 65% express another UV-sensitive Rhodopsin encoded by Rh4. | Rhodopsin 5 (Rh5) encodes a visual GPCR opsin that covalently binds the chromophore retinal. A photon of light stimulates the isomerization of retinal resulting in a conformational change in the product of Rh5 and signal activation. Its peak sensitivity is in the blue and it is expressed in a subclass of R8 photoreceptors; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. | 0.540 |
| Rh3 | Rh6 | FBpp0083284 | FBpp0312616 | Rhodopsin 3 (Rh3) encodes a Rhodopsin GPCR protein that responds to UV light and activates the phototransduction cascade that leads to photoreceptor depolarization. Rh3 is expressed in R7 photoreceptors in a stochastic manner: 35% of R7 photoreceptors express Rh3 while the remaining 65% express another UV-sensitive Rhodopsin encoded by Rh4. | Opsin Rh6; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. | 0.598 |
| Rh3 | dve | FBpp0083284 | FBpp0071689 | Rhodopsin 3 (Rh3) encodes a Rhodopsin GPCR protein that responds to UV light and activates the phototransduction cascade that leads to photoreceptor depolarization. Rh3 is expressed in R7 photoreceptors in a stochastic manner: 35% of R7 photoreceptors express Rh3 while the remaining 65% express another UV-sensitive Rhodopsin encoded by Rh4. | Defective proventriculus (dve) encodes a transcriptional repressor that binds to the K50 site. It is involved in developmental patterning, cell-type specification, and functional differentiation. | 0.669 |
| Rh3 | oc | FBpp0083284 | FBpp0423136 | Rhodopsin 3 (Rh3) encodes a Rhodopsin GPCR protein that responds to UV light and activates the phototransduction cascade that leads to photoreceptor depolarization. Rh3 is expressed in R7 photoreceptors in a stochastic manner: 35% of R7 photoreceptors express Rh3 while the remaining 65% express another UV-sensitive Rhodopsin encoded by Rh4. | Homeotic protein ocelliless; Transcriptional regulator involved in pattern formation and cell determination in the embryonic CNS and larval imaginal disks. Also later in development to coordinate the expression of regulatory and structural genes required for photoreceptor cell fate in the ocelli. Has a dual role in the terminal differentiation of subtypes of photoreceptors by regulating rhodopsin (rh) expression: essential for establishing the expression of rh genes in the pale subset of ommatidia as well as repressing Rh6 in outer photoreceptors. Belongs to the paired homeobox family. | 0.827 |
| Rh4 | Pph13 | FBpp0075097 | FBpp0077730 | Opsin Rh4; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. | PvuII-PstI homology 13 (Pph13) encodes a paired-class homeodomain protein. It is critical for rhabdomeric photoreceptor differentiation, phototransduction and rhabdomere morphogenesis. | 0.689 |
| Rh4 | Rh3 | FBpp0075097 | FBpp0083284 | Opsin Rh4; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. | Rhodopsin 3 (Rh3) encodes a Rhodopsin GPCR protein that responds to UV light and activates the phototransduction cascade that leads to photoreceptor depolarization. Rh3 is expressed in R7 photoreceptors in a stochastic manner: 35% of R7 photoreceptors express Rh3 while the remaining 65% express another UV-sensitive Rhodopsin encoded by Rh4. | 0.845 |
| Rh4 | Rh5 | FBpp0075097 | FBpp0309539 | Opsin Rh4; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. | Rhodopsin 5 (Rh5) encodes a visual GPCR opsin that covalently binds the chromophore retinal. A photon of light stimulates the isomerization of retinal resulting in a conformational change in the product of Rh5 and signal activation. Its peak sensitivity is in the blue and it is expressed in a subclass of R8 photoreceptors; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. | 0.448 |
| Rh4 | Rh6 | FBpp0075097 | FBpp0312616 | Opsin Rh4; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. | Opsin Rh6; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. | 0.531 |