STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EMC8-9ER Membrane protein Complex 8-9 (EMC8-9) encodes a subunit of the ER membrane protein complex (EMC). In fly retinas, EMC has been shown to be essential for the biosynthesis of multi-pass membrane proteins, but not for single-pass membrane proteins and secretory proteins. (203 aa)    
Predicted Functional Partners:
EMC3
ER Membrane protein Complex 3 (EMC3) encodes a subunit of the ER membrane protein complex (EMC). In fly retinas, EMC has been shown to be essential for the biosynthesis of multi-pass membrane proteins, but not for single-pass membrane proteins and secretory proteins.
   
 0.997
EMC2B
GH23451p.
   
 0.996
EMC2A
LD10670p.
   
 0.994
EMC4
ER membrane protein complex subunit 4; Belongs to the EMC4 family.
   
 0.994
EMC1
ER Membrane protein Complex 1 (EMC1) encodes a subunit of the ER membrane protein complex (EMC). In fly retinas, EMC has been shown to be essential for the biosynthesis of multi-pass membrane proteins, but not for single-pass membrane proteins and secretory proteins.
   
 0.991
EMC7
DUF2012 domain-containing protein; Carbohydrate binding.
   
 0.990
EMC10
Uncharacterized protein, isoform C.
   
 0.989
EMC6
Uncharacterized protein; It is involved in the biological process described with: autophagosome assembly.
   
 0.986
EMC5
GEO07313p1; Inorganic cation transmembrane transporter activity.
   
 0.979
CG30274
Uncharacterized protein; Creatine kinase activity; kinase activity. It is involved in the biological process described with: phosphocreatine biosynthetic process; Belongs to the ATP:guanido phosphotransferase family.
      
 0.794
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.