Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CG9876FI01017p; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. (275 aa)    
Predicted Functional Partners:
TbCMF46
TbCMF46.
   
   0.830
Osi10
Osiris 10.
   
    0.820
CG10280
Metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.
   
    0.814
Nach
Sodium channel protein Nach; Nach (Nach) encodes a predicted member of the Degenerin/Epithelial Sodium Channel family of proteins. It is mainly expressed in the tracheal system and functions in liquid clearance during tracheal development; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
   
    0.811
CG42366
Uncharacterized protein, isoform A; Protein kinase activity; MAP kinase activity; ATP binding. It is involved in the biological process described with: cilium assembly; intraciliary transport; intracellular signal transduction; protein phosphorylation; regulation of gene expression.
   
    0.792
Gr98c
Putative gustatory receptor 98c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates; Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr2a subfamily.
   
    0.790
Ir7a
Ionotropic receptor 7a; Ligand-gated ion channel activity. It is involved in the biological process described with: detection of chemical stimulus involved in sensory perception of bitter taste; sensory perception of taste; detection of chemical stimulus.
   
   0.789
CG13634
Uncharacterized protein.
   
    0.788
Gr36c
Putative gustatory receptor 36c; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
   
    0.786
CG5078
MFS domain-containing protein; Transporter activity. It is involved in the biological process described with: transmembrane transport.
   
    0.781
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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