Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yellow-dGH10609p. (432 aa)    
Predicted Functional Partners:
e
LP19442p; Ebony (e) encodes a protein that links beta-alanine to biogenic amines like dopamine or histamine. It controls the amount of free biogenic amine, e.g. of dopamine in cuticle formation and of histamine in visual signal transduction of the eye. It is also involved in behavioral rhythmicity.
      
 0.616
Ag5r
Antigen 5-related, isoform A; It is involved in the biological process described with: multicellular organism reproduction.
   
  
 0.503
fzr
Fizzy-related, isoform A; Fizzy-related (fzr) encodes a protein that binds to the Anaphase-Promoting Complex/Cyclosome (APC/C) ubiquitin ligase to stimulate its activity during G1 phase.
    
   0.452
AANAT1
Dopamine N-acetyltransferase; Catalyzes N-acetylation of tryptamine, tyramine, dopamine, serotonin and octopamine. Is not essential for sclerotization.
   
  
 0.425
CG17764
Uncharacterized protein; It is involved in the biological process described with: mRNA splicing, via spliceosome.
      
 0.423
yellow-c
Yellow-c, isoform A.
  
  
0.420
yellow-f2
L-dopachrome tautomerase yellow-f2; Tautomerization of L-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI). Also catalyzes the tautomerization of the methyl ester of L-dopachrome and dopamine chrome. May play a role in melanization reactions during late pupal and adult stages. Belongs to the major royal jelly protein family.
  
  
0.410
yellow-e
RE55542p.
  
   
0.400
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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