yellow-d protein (Drosophila melanogaster) - STRING interaction network

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gene neighborhood

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protein homology

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Score

yellow-d

GH10609p. (432 aa)

Predicted Functional Partners:

e

0.675

Ag5r

0.499

CG17764

0.424

AANAT1

0.417

KFase

0.415

yellow-f2

0.412

cn

0.411

yellow-g

0.404

Your Current Organism:

Drosophila melanogaster

NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AANAT1	e	FBpp0089101	FBpp0083505	Dopamine N-acetyltransferase; Catalyzes N-acetylation of tryptamine, tyramine, dopamine, serotonin and octopamine. Is not essential for sclerotization.	LP19442p; Ebony (e) encodes a protein that links beta-alanine to biogenic amines like dopamine or histamine. It controls the amount of free biogenic amine, e.g. of dopamine in cuticle formation and of histamine in visual signal transduction of the eye. It is also involved in behavioral rhythmicity.	0.851
AANAT1	yellow-d	FBpp0089101	FBpp0071920	Dopamine N-acetyltransferase; Catalyzes N-acetylation of tryptamine, tyramine, dopamine, serotonin and octopamine. Is not essential for sclerotization.	GH10609p.	0.417
AANAT1	yellow-f2	FBpp0089101	FBpp0082190	Dopamine N-acetyltransferase; Catalyzes N-acetylation of tryptamine, tyramine, dopamine, serotonin and octopamine. Is not essential for sclerotization.	L-dopachrome tautomerase yellow-f2; Tautomerization of L-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI). Also catalyzes the tautomerization of the methyl ester of L-dopachrome and dopamine chrome. May play a role in melanization reactions during late pupal and adult stages. Belongs to the major royal jelly protein family.	0.423
Ag5r	yellow-d	FBpp0305814	FBpp0071920	Antigen 5-related, isoform A; It is involved in the biological process described with: multicellular organism reproduction.	GH10609p.	0.499
CG17764	yellow-d	FBpp0070724	FBpp0071920	Uncharacterized protein; It is involved in the biological process described with: mRNA splicing, via spliceosome.	GH10609p.	0.424
KFase	cn	FBpp0308832	FBpp0311059	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.	Kynurenine 3-monooxygenase; Cinnabar (cn) encodes the enzyme that synthesizes 3-hydroxykynurenine (3-HK) as part of the kynurenine pathway of tryptophan degradation. 3-HK is an intermediate product in the formation of ommochromes, the brown pigments in the fly eye, and thus cn loss of function mutant flies exhibit altered eye color. Several kynurenine pathway metabolites are neuroactive and have been linked to the pathogenesis of neurodegenerative disorders.	0.992
KFase	e	FBpp0308832	FBpp0083505	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.	LP19442p; Ebony (e) encodes a protein that links beta-alanine to biogenic amines like dopamine or histamine. It controls the amount of free biogenic amine, e.g. of dopamine in cuticle formation and of histamine in visual signal transduction of the eye. It is also involved in behavioral rhythmicity.	0.581
KFase	yellow-d	FBpp0308832	FBpp0071920	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.	GH10609p.	0.415
KFase	yellow-f2	FBpp0308832	FBpp0082190	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.	L-dopachrome tautomerase yellow-f2; Tautomerization of L-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI). Also catalyzes the tautomerization of the methyl ester of L-dopachrome and dopamine chrome. May play a role in melanization reactions during late pupal and adult stages. Belongs to the major royal jelly protein family.	0.549
cn	KFase	FBpp0311059	FBpp0308832	Kynurenine 3-monooxygenase; Cinnabar (cn) encodes the enzyme that synthesizes 3-hydroxykynurenine (3-HK) as part of the kynurenine pathway of tryptophan degradation. 3-HK is an intermediate product in the formation of ommochromes, the brown pigments in the fly eye, and thus cn loss of function mutant flies exhibit altered eye color. Several kynurenine pathway metabolites are neuroactive and have been linked to the pathogenesis of neurodegenerative disorders.	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.	0.992
cn	yellow-d	FBpp0311059	FBpp0071920	Kynurenine 3-monooxygenase; Cinnabar (cn) encodes the enzyme that synthesizes 3-hydroxykynurenine (3-HK) as part of the kynurenine pathway of tryptophan degradation. 3-HK is an intermediate product in the formation of ommochromes, the brown pigments in the fly eye, and thus cn loss of function mutant flies exhibit altered eye color. Several kynurenine pathway metabolites are neuroactive and have been linked to the pathogenesis of neurodegenerative disorders.	GH10609p.	0.411
e	AANAT1	FBpp0083505	FBpp0089101	LP19442p; Ebony (e) encodes a protein that links beta-alanine to biogenic amines like dopamine or histamine. It controls the amount of free biogenic amine, e.g. of dopamine in cuticle formation and of histamine in visual signal transduction of the eye. It is also involved in behavioral rhythmicity.	Dopamine N-acetyltransferase; Catalyzes N-acetylation of tryptamine, tyramine, dopamine, serotonin and octopamine. Is not essential for sclerotization.	0.851
e	KFase	FBpp0083505	FBpp0308832	LP19442p; Ebony (e) encodes a protein that links beta-alanine to biogenic amines like dopamine or histamine. It controls the amount of free biogenic amine, e.g. of dopamine in cuticle formation and of histamine in visual signal transduction of the eye. It is also involved in behavioral rhythmicity.	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.	0.581
e	yellow-d	FBpp0083505	FBpp0071920	LP19442p; Ebony (e) encodes a protein that links beta-alanine to biogenic amines like dopamine or histamine. It controls the amount of free biogenic amine, e.g. of dopamine in cuticle formation and of histamine in visual signal transduction of the eye. It is also involved in behavioral rhythmicity.	GH10609p.	0.675
e	yellow-f2	FBpp0083505	FBpp0082190	LP19442p; Ebony (e) encodes a protein that links beta-alanine to biogenic amines like dopamine or histamine. It controls the amount of free biogenic amine, e.g. of dopamine in cuticle formation and of histamine in visual signal transduction of the eye. It is also involved in behavioral rhythmicity.	L-dopachrome tautomerase yellow-f2; Tautomerization of L-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI). Also catalyzes the tautomerization of the methyl ester of L-dopachrome and dopamine chrome. May play a role in melanization reactions during late pupal and adult stages. Belongs to the major royal jelly protein family.	0.672
yellow-d	AANAT1	FBpp0071920	FBpp0089101	GH10609p.	Dopamine N-acetyltransferase; Catalyzes N-acetylation of tryptamine, tyramine, dopamine, serotonin and octopamine. Is not essential for sclerotization.	0.417
yellow-d	Ag5r	FBpp0071920	FBpp0305814	GH10609p.	Antigen 5-related, isoform A; It is involved in the biological process described with: multicellular organism reproduction.	0.499
yellow-d	CG17764	FBpp0071920	FBpp0070724	GH10609p.	Uncharacterized protein; It is involved in the biological process described with: mRNA splicing, via spliceosome.	0.424
yellow-d	KFase	FBpp0071920	FBpp0308832	GH10609p.	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.	0.415
yellow-d	cn	FBpp0071920	FBpp0311059	GH10609p.	Kynurenine 3-monooxygenase; Cinnabar (cn) encodes the enzyme that synthesizes 3-hydroxykynurenine (3-HK) as part of the kynurenine pathway of tryptophan degradation. 3-HK is an intermediate product in the formation of ommochromes, the brown pigments in the fly eye, and thus cn loss of function mutant flies exhibit altered eye color. Several kynurenine pathway metabolites are neuroactive and have been linked to the pathogenesis of neurodegenerative disorders.	0.411