| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DMAP1 | Gas41 | FBpp0085546 | FBpp0078992 | DNA methyltransferase 1-associated protein 1; Involved in transcription repression and activation (By similarity). Required for larvae and pupal development, and for normal innate immune responses. Involved in modulating the activation of the immune deficiency pathway (Imd), acting either downstream of, or at the level of, the NF-kappa-B factor Rel. Possibly functions with akirin to regulate Rel, and its interaction with the Brahma complex protein Bap55 suggests that it may regulate the IMD pathway at the level of chromatin remodeling. | LD16161p; Gas41 (Gas41) encodes a protein that contributes to histone acetylation and is involved in chromatin organization and RNA interference. | 0.999 |
| DMAP1 | rept | FBpp0085546 | FBpp0074756 | DNA methyltransferase 1-associated protein 1; Involved in transcription repression and activation (By similarity). Required for larvae and pupal development, and for normal innate immune responses. Involved in modulating the activation of the immune deficiency pathway (Imd), acting either downstream of, or at the level of, the NF-kappa-B factor Rel. Possibly functions with akirin to regulate Rel, and its interaction with the Brahma complex protein Bap55 suggests that it may regulate the IMD pathway at the level of chromatin remodeling. | RuvB-like helicase 2; Acts as a transcriptional coactivator in Wg signaling caused by altered arm signaling. Pont and rept interfere antagonistically with nuclear arm signaling function, and are required to enhance or reduce arm activity, respectively. Also an essential cofactor for the normal function of Myc; required for cellular proliferation and growth. | 0.999 |
| DMAP1 | tbrd-2 | FBpp0085546 | FBpp0085699 | DNA methyltransferase 1-associated protein 1; Involved in transcription repression and activation (By similarity). Required for larvae and pupal development, and for normal innate immune responses. Involved in modulating the activation of the immune deficiency pathway (Imd), acting either downstream of, or at the level of, the NF-kappa-B factor Rel. Possibly functions with akirin to regulate Rel, and its interaction with the Brahma complex protein Bap55 suggests that it may regulate the IMD pathway at the level of chromatin remodeling. | Testis-specifically expressed bromodomain containing protein-2 (tbrd-2) encodes a protein required for male fertility. It interacts with the products of tbrd-1, tbrd-3 and testis-specific TAFs. | 0.705 |
| DMAP1 | tbrd-3 | FBpp0085546 | FBpp0071950 | DNA methyltransferase 1-associated protein 1; Involved in transcription repression and activation (By similarity). Required for larvae and pupal development, and for normal innate immune responses. Involved in modulating the activation of the immune deficiency pathway (Imd), acting either downstream of, or at the level of, the NF-kappa-B factor Rel. Possibly functions with akirin to regulate Rel, and its interaction with the Brahma complex protein Bap55 suggests that it may regulate the IMD pathway at the level of chromatin remodeling. | Testis-specifically expressed bromodomain containing protein-3 (tbrd-3) encodes a protein that interacts with the products of tbrd-1, tbrd-2 and testis-specific TAFs. | 0.705 |
| Gas41 | DMAP1 | FBpp0078992 | FBpp0085546 | LD16161p; Gas41 (Gas41) encodes a protein that contributes to histone acetylation and is involved in chromatin organization and RNA interference. | DNA methyltransferase 1-associated protein 1; Involved in transcription repression and activation (By similarity). Required for larvae and pupal development, and for normal innate immune responses. Involved in modulating the activation of the immune deficiency pathway (Imd), acting either downstream of, or at the level of, the NF-kappa-B factor Rel. Possibly functions with akirin to regulate Rel, and its interaction with the Brahma complex protein Bap55 suggests that it may regulate the IMD pathway at the level of chromatin remodeling. | 0.999 |
| Gas41 | Taf1 | FBpp0078992 | FBpp0293442 | LD16161p; Gas41 (Gas41) encodes a protein that contributes to histone acetylation and is involved in chromatin organization and RNA interference. | Transcription initiation factor TFIID subunit 1; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp. | 0.962 |
| Gas41 | Taf7 | FBpp0078992 | FBpp0081253 | LD16161p; Gas41 (Gas41) encodes a protein that contributes to histone acetylation and is involved in chromatin organization and RNA interference. | Transcription initiation factor TFIID subunit 7; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | 0.931 |
| Gas41 | rept | FBpp0078992 | FBpp0074756 | LD16161p; Gas41 (Gas41) encodes a protein that contributes to histone acetylation and is involved in chromatin organization and RNA interference. | RuvB-like helicase 2; Acts as a transcriptional coactivator in Wg signaling caused by altered arm signaling. Pont and rept interfere antagonistically with nuclear arm signaling function, and are required to enhance or reduce arm activity, respectively. Also an essential cofactor for the normal function of Myc; required for cellular proliferation and growth. | 0.999 |
| Gas41 | sa | FBpp0078992 | FBpp0078055 | LD16161p; Gas41 (Gas41) encodes a protein that contributes to histone acetylation and is involved in chromatin organization and RNA interference. | Spermatocyte arrest (sa) encodes a testis binding protein associated factor involved in control of the male meiotic cycle, gene expression regulation, and spermatid differentiation. | 0.927 |
| Gas41 | tbrd-2 | FBpp0078992 | FBpp0085699 | LD16161p; Gas41 (Gas41) encodes a protein that contributes to histone acetylation and is involved in chromatin organization and RNA interference. | Testis-specifically expressed bromodomain containing protein-2 (tbrd-2) encodes a protein required for male fertility. It interacts with the products of tbrd-1, tbrd-3 and testis-specific TAFs. | 0.724 |
| Gas41 | tbrd-3 | FBpp0078992 | FBpp0071950 | LD16161p; Gas41 (Gas41) encodes a protein that contributes to histone acetylation and is involved in chromatin organization and RNA interference. | Testis-specifically expressed bromodomain containing protein-3 (tbrd-3) encodes a protein that interacts with the products of tbrd-1, tbrd-2 and testis-specific TAFs. | 0.724 |
| NSD | tbrd-2 | FBpp0084636 | FBpp0085699 | Probable histone-lysine N-methyltransferase Mes-4; Probable histone methyltransferase. Histone methylation gives specific tags for epigenetic transcriptional activation or repression (By similarity); Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | Testis-specifically expressed bromodomain containing protein-2 (tbrd-2) encodes a protein required for male fertility. It interacts with the products of tbrd-1, tbrd-3 and testis-specific TAFs. | 0.677 |
| NSD | tbrd-3 | FBpp0084636 | FBpp0071950 | Probable histone-lysine N-methyltransferase Mes-4; Probable histone methyltransferase. Histone methylation gives specific tags for epigenetic transcriptional activation or repression (By similarity); Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | Testis-specifically expressed bromodomain containing protein-3 (tbrd-3) encodes a protein that interacts with the products of tbrd-1, tbrd-2 and testis-specific TAFs. | 0.677 |
| PSR | tbrd-2 | FBpp0303404 | FBpp0085699 | Bifunctional arginine demethylase and lysyl-hydroxylase PSR; Dioxygenase that can both act as a histone arginine demethylase and a lysyl-hydroxylase. | Testis-specifically expressed bromodomain containing protein-2 (tbrd-2) encodes a protein required for male fertility. It interacts with the products of tbrd-1, tbrd-3 and testis-specific TAFs. | 0.676 |
| PSR | tbrd-3 | FBpp0303404 | FBpp0071950 | Bifunctional arginine demethylase and lysyl-hydroxylase PSR; Dioxygenase that can both act as a histone arginine demethylase and a lysyl-hydroxylase. | Testis-specifically expressed bromodomain containing protein-3 (tbrd-3) encodes a protein that interacts with the products of tbrd-1, tbrd-2 and testis-specific TAFs. | 0.676 |
| Taf1 | Gas41 | FBpp0293442 | FBpp0078992 | Transcription initiation factor TFIID subunit 1; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp. | LD16161p; Gas41 (Gas41) encodes a protein that contributes to histone acetylation and is involved in chromatin organization and RNA interference. | 0.962 |
| Taf1 | Taf7 | FBpp0293442 | FBpp0081253 | Transcription initiation factor TFIID subunit 1; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp. | Transcription initiation factor TFIID subunit 7; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | 0.999 |
| Taf1 | rept | FBpp0293442 | FBpp0074756 | Transcription initiation factor TFIID subunit 1; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp. | RuvB-like helicase 2; Acts as a transcriptional coactivator in Wg signaling caused by altered arm signaling. Pont and rept interfere antagonistically with nuclear arm signaling function, and are required to enhance or reduce arm activity, respectively. Also an essential cofactor for the normal function of Myc; required for cellular proliferation and growth. | 0.513 |
| Taf1 | sa | FBpp0293442 | FBpp0078055 | Transcription initiation factor TFIID subunit 1; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp. | Spermatocyte arrest (sa) encodes a testis binding protein associated factor involved in control of the male meiotic cycle, gene expression regulation, and spermatid differentiation. | 0.992 |
| Taf1 | tbrd-2 | FBpp0293442 | FBpp0085699 | Transcription initiation factor TFIID subunit 1; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp. | Testis-specifically expressed bromodomain containing protein-2 (tbrd-2) encodes a protein required for male fertility. It interacts with the products of tbrd-1, tbrd-3 and testis-specific TAFs. | 0.682 |
