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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG13559FI16602p1; It is involved in the biological process described with: positive regulation of hemocyte proliferation. (114 aa)    
Predicted Functional Partners:
CG1572
LD04844p; It is involved in the biological process described with: positive regulation of hemocyte proliferation.
      
 0.837
Galphaf
G protein alpha f subunit (Galphaf) encodes a transcriptional target of the JAK/STAT pathway in blood cells where it regulates cell shape and function; Belongs to the G-alpha family.
      
 0.602
Rab30
Rab30, isoform A; Rab30 (Rab30) encodes a JNK transcriptional target. It is involved in JNK-mediated processes such as dorsal closure, embryonic head involution and thorax closure.
      
 0.491
Socs36E
Suppressor of cytokine signaling at 36E (Socs36E) encodes a negative regulator of the JAK/STAT and EGFR pathways. It is a transcriptional target of the product of Stat92E that mediates lysosomal degradation following pathway stimulation and inhibits basal pathway activity.
      
 0.437
Gadd45
Growth arrest and DNA damage-inducible 45; It is involved in the biological process described with: regulation of oviposition; activation of MAPKKK activity; JNK cascade; regulation of cell cycle.
      
 0.433
vir-1
Virus-induced RNA 1 (vir-1) is produced from a promoter that is induced by viral infection. It can be used as a marker of the induction of an antiviral response. Its expression is regulated by the Jak/STAT pathway.
      
 0.424
gcm
Glial cells missing (gcm) encodes an essential zinc finger transcription factor that determines the fate of the lateral glial cells. It is involved in the differentiation of plasmatocytes, tendon cells and specific neurons.
      
 0.424
Ptp61F
Tyrosine-protein phosphatase non-receptor type 61F; Non-receptor protein tyrosine phosphatase required for maintaining Dock in its non-phosphorylated state.
      
 0.400
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.