CG12491 protein (fruit fly) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

CG12491

Uncharacterized protein. (157 aa)

Predicted Functional Partners:

CG14852

0.928

CG8087

0.919

CG14851

0.918

CG13135

0.913

CG11300

0.718

CG14850

0.679

pAbp

0.618

CG3918

0.572

CG9004

0.572

AP-2mu

0.572

Your Current Organism:

Drosophila melanogaster

NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP-2mu	CG12491	FBpp0083646	FBpp0071998	Adaptor Protein complex 2, mu subunit (AP-2mu) encodes a component of the AP-2 adaptor complex, which recruits certain transmembrane proteins into clathrin-coated pits for endocytic internalization.	Uncharacterized protein.	0.572
CG11300	CG12491	FBpp0071999	FBpp0071998	GEO09102p1.	Uncharacterized protein.	0.718
CG11300	CG13135	FBpp0071999	FBpp0308595	GEO09102p1.	Uncharacterized protein, isoform A.	0.918
CG11300	CG14850	FBpp0071999	FBpp0082414	GEO09102p1.	Uncharacterized protein.	0.754
CG11300	CG14851	FBpp0071999	FBpp0082415	GEO09102p1.	MIP29828p.	0.922
CG11300	CG14852	FBpp0071999	FBpp0082416	GEO09102p1.	Uncharacterized protein.	0.951
CG11300	CG8087	FBpp0071999	FBpp0082442	GEO09102p1.	GEO02335p1.	0.940
CG12491	AP-2mu	FBpp0071998	FBpp0083646	Uncharacterized protein.	Adaptor Protein complex 2, mu subunit (AP-2mu) encodes a component of the AP-2 adaptor complex, which recruits certain transmembrane proteins into clathrin-coated pits for endocytic internalization.	0.572
CG12491	CG11300	FBpp0071998	FBpp0071999	Uncharacterized protein.	GEO09102p1.	0.718
CG12491	CG13135	FBpp0071998	FBpp0308595	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.913
CG12491	CG14850	FBpp0071998	FBpp0082414	Uncharacterized protein.	Uncharacterized protein.	0.679
CG12491	CG14851	FBpp0071998	FBpp0082415	Uncharacterized protein.	MIP29828p.	0.918
CG12491	CG14852	FBpp0071998	FBpp0082416	Uncharacterized protein.	Uncharacterized protein.	0.928
CG12491	CG3918	FBpp0071998	FBpp0070874	Uncharacterized protein.	LD15209p; Nucleic acid binding; zinc ion binding.	0.572
CG12491	CG8087	FBpp0071998	FBpp0082442	Uncharacterized protein.	GEO02335p1.	0.919
CG12491	CG9004	FBpp0071998	FBpp0072768	Uncharacterized protein.	Nucleolar MIF4G domain-containing protein 1 homolog; RNA binding. It is involved in the biological process described with: ribosomal small subunit biogenesis.	0.572
CG12491	pAbp	FBpp0071998	FBpp0085919	Uncharacterized protein.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Since it interacts with the cap-associating translation initiation factor eIF4G, it is likely that it functions by linking Atx2 to the cap-binding complex. Forms a complex with tyf and Atx2 which functions in adult circadian pacemaker neurons to sustain circadian rhythms likely by switching between activator and repressor modes of post-transcriptional regulation via interaction with Lsm12a or me31B, respectively. The activator complex (Atx2-tyf activator complex) activates the TYF-dependent translation of per to maintain 24 [...]	0.618
CG13135	CG11300	FBpp0308595	FBpp0071999	Uncharacterized protein, isoform A.	GEO09102p1.	0.918
CG13135	CG12491	FBpp0308595	FBpp0071998	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.913
CG13135	CG14850	FBpp0308595	FBpp0082414	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.772