Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CG18128FI08065p; Purine-nucleoside phosphorylase activity. It is involved in the biological process described with: nucleoside metabolic process. (339 aa)    
Predicted Functional Partners:
Aprt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.960
Adk1
AT16233p; Adenosine kinase activity. It is involved in the biological process described with: purine ribonucleoside salvage; AMP biosynthetic process.
  
 
 0.957
Adk2
Adenosine kinase activity. It is involved in the biological process described with: purine ribonucleoside salvage; AMP biosynthetic process.
    
 0.952
Adk3
GM02629p; Adenosine kinase activity.
    
 0.950
dnk
Deoxynucleoside kinase; Deoxyribonucleoside kinase that has a broad specificity phosphorylating thymidine, 2'-deoxyriboadenosine, 2'-deoxyribocytidine and 2'-deoxyriboguanosine. Specificity is higher for pyrimidine nucleosides. Several anti-viral and anti-cancer nucleoside analogs are also efficiently phosphorylated.
     
 0.949
DhpD
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. Also has 7,8-dihydropterin deaminase activity, which plays a role in synthesis of the red eye pigment aurodrosopterin.
  
 
 0.938
Adgf-E
Adenosine deaminase-related growth factor E; It is involved in the biological process described with: inosine biosynthetic process.
  
 
 0.933
Adgf-B
Adenosine deaminase-related growth factor B; Adenosine deaminase activity. It is involved in the biological process described with: inosine biosynthetic process; adenosine catabolic process.
  
 
 0.928
Adgf-A2
Adenosine deaminase-related growth factor A2 (Adgf-A2) encodes a growth factor involved in spermatid development.
  
 
 0.926
Adgf-A
Adenosine deaminase-related growth factor A (Adgf-A) encodes an extracellular deaminase that regulates the level of extracellular adenosine by converting adenosine to inosine. This activity is important for regulation of systemic metabolism, especially during stress and infection.
    
 0.920
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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