Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CG5569SD18780p; It is involved in the biological process described with: mitochondrial respiratory chain complex I assembly. (196 aa)    
Predicted Functional Partners:
CG11722
Protein NDUFAF4 homolog; It is involved in the biological process described with: mitochondrial respiratory chain complex I assembly; Belongs to the NDUFAF4 family.
   
 0.999
140up
RPII140-upstream gene protein; Essential for viability.
   
 0.994
CIA30
Complex I intermediate-associated protein 30, mitochondrial; Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
   
 0.992
ND-B16.6
NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone.
   
 0.980
ND-23
NADH dehydrogenase (Ubiquinone) 23 kDa subunit; NADH dehydrogenase activity; 4 iron, 4 sulfur cluster binding. It is involved in the biological process described with: aerobic respiration; mitochondrial ATP synthesis coupled electron transport; mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly.
   
 0.979
ND-19
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
   
 0.973
ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Involved in the innate immune response. Promotes the production of antibacterial peptides; Belongs to the ECSIT family.
   
 0.972
ND-30
NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. It is involved in the biological process described with: oxidation-reduction process; reactive oxygen species metabolic process; Belongs to the complex I 30 kDa subunit family.
   
 0.969
CG8067
LD45826p; Methyltransferase activity.
   
 0.969
ND-PDSW
NADH dehydrogenase (Ubiquinone) PDSW subunit, isoform A; NADH dehydrogenase activity. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone.
   
 0.965
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.