Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CG3492GH18016p; Peptidyl-prolyl cis-trans isomerase activity; cyclosporin A binding. It is involved in the biological process described with: protein folding; protein peptidyl-prolyl isomerization. (404 aa)    
Predicted Functional Partners:
CG1324
GH11587p.
   
  
 0.876
CG3494
Uncharacterized protein, isoform A.
   
 
 0.872
CG3483
CG3483 protein; Isocitrate dehydrogenase (NAD+) activity. It is involved in the biological process described with: isocitrate metabolic process; tricarboxylic acid cycle.
  
 
 0.869
CG16837
GEO02361p1; Dynein intermediate chain binding. It is involved in the biological process described with: microtubule-based movement.
   
 
 0.864
loopin-1
Loopin-1, isoform A; Loopin-1 (loopin-1) encodes a testis-specific protein with homology to several leucine aminopeptidases. Sequence analysis suggest that it doesn't have enzymatic activity. It accumulates inside the axoneme-associated mitochondrial derivative in mature sperms.
   
  
 0.863
CG15873
Peptidase S1 domain-containing protein; It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
   
 
 0.856
CG1314
FI09604p.
   
  
 0.837
CG11227
Uncharacterized protein, isoform B.
   
 
 0.835
CG15452
IP07141p.
   
  
 0.826
CG15710
IP01184p; DNA-binding transcription factor activity; transcription regulatory region sequence-specific DNA binding. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II.
   
  
 0.821
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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