STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG3492GH18016p; Peptidyl-prolyl cis-trans isomerase activity; cyclosporin A binding. It is involved in the biological process described with: protein folding; protein peptidyl-prolyl isomerization. (404 aa)    
Predicted Functional Partners:
CG1324
GH11587p.
   
  
 0.916
loopin-1
Loopin-1, isoform A; Loopin-1 (loopin-1) encodes a testis-specific protein with homology to several leucine aminopeptidases. Sequence analysis suggest that it doesn't have enzymatic activity. It accumulates inside the axoneme-associated mitochondrial derivative in mature sperms.
   
  
 0.911
CG3494
Uncharacterized protein, isoform A.
   
 
 0.898
CG3483
CG3483 protein; Isocitrate dehydrogenase (NAD+) activity. It is involved in the biological process described with: isocitrate metabolic process; tricarboxylic acid cycle.
  
  
 0.889
CG15873
Peptidase S1 domain-containing protein; It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
   
  
 0.865
CG1314
FI09604p.
   
  
 0.863
CG16837
GEO02361p1; Dynein intermediate chain binding. It is involved in the biological process described with: microtubule-based movement.
   
  
 0.860
CG11227
Uncharacterized protein, isoform B.
   
 
 0.840
CG15710
IP01184p; DNA-binding transcription factor activity; transcription regulatory region sequence-specific DNA binding. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II.
   
 
 0.837
CG15452
IP07141p.
   
  
 0.835
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.