Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Usp15-31Ubiquitin specific protease 15/31 (Usp15-31) encodes a ubiquitin C-terminal hydrolase that is involved in the positive regulation of the apoptosome components encoded by Dark and Dronc; Belongs to the peptidase C19 family. (1272 aa)    
Predicted Functional Partners:
Usp30
Ubiquitin carboxyl-terminal hydrolase 30 homolog; Deubiquitinating enzyme that acts as a key inhibitor of mitophagy by counteracting the action of parkin (park). Belongs to the peptidase C19 family.
   
 
 0.942
Usp14
Ubiquitin carboxyl-terminal hydrolase; Ubiquitin specific protease 14 (Usp14) encodes a deubiquitinase that associates with the 19S component of the proteasome in a reversible manner. Its functions include ubiquitin chain disassemblance for mono-ubiquitin recycling, control of protein degradation by the proteasome and regulation of proteasome subtrate interactions.
    
 
 0.921
CG32533
LD31543p; RNA binding; helicase activity. It is involved in the biological process described with: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.
   
 
 0.886
Usp7
Ubiquitin carboxyl-terminal hydrolase 7; Hydrolase that deubiquitinates target proteins.
   
 
 0.862
Usp5
Ubiquitin carboxyl-terminal hydrolase; Ubiquitin specific protease 5 (Usp5) encodes an essential enzyme that cleaves unanchored lysine48-linked polyubiquitin chains. It is involved in photoreceptor differentiation, neuron pathfinding and apoptosis.
    
 
 0.794
TyrRS
tRNA binding; tyrosine-tRNA ligase activity; ATP binding. It is involved in the biological process described with: tyrosyl-tRNA aminoacylation.
      
 0.742
mRpS9
Mitochondrial ribosomal protein S9; RNA binding; structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation.
   
 
 0.727
CYLD
Cylindromatosis, isoform D; Lys63-specific deubiquitinase activity; thiol-dependent ubiquitin-specific protease activity; ubiquitinyl hydrolase activity, acting on linear ubiquitin.
      
 0.706
mRpL3
Mitochondrial ribosomal protein L3; Structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; translation.
   
 
 0.699
PCNA
Proliferating cell nuclear antigen; Likely to be an auxiliary protein of DNA polymerase delta complex and is probably involved in the control of DNA replication and repair by increasing the polymerase's processibility. Belongs to the PCNA family.
   
 0.695
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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