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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppm1AT28366p; Cation binding; protein serine/threonine phosphatase activity; magnesium-dependent protein serine/threonine phosphatase activity; phosphoprotein phosphatase activity. It is involved in the biological process described with: protein dephosphorylation. (352 aa)    
Predicted Functional Partners:
CG7886
Protein Cep78 homolog; May play a role in cilium biogenesis. Belongs to the CEP78 family.
   
 
 0.837
Lrrk
Leucine-rich repeat kinase (Lrrk) encodes a large Ser/Thr kinase involved in mRNA translational control, cytoskeleton regulation, vesicle trafficking, autophagy, and immune response.
  
 
 0.832
CG9389
GH15479p; Inositol monophosphate 1-phosphatase activity. It is involved in the biological process described with: inositol metabolic process; signal transduction; inositol phosphate dephosphorylation; phosphatidylinositol phosphorylation.
   
    0.789
CG15742
Uncharacterized protein, isoform A.
   
 
 0.756
CG3982
Uncharacterized protein.
   
    0.744
CG6380
AT25465p; Protein phosphatase inhibitor activity. It is involved in the biological process described with: regulation of phosphoprotein phosphatase activity; regulation of signal transduction.
   
  
 0.740
CG15306
Uncharacterized protein, isoform A; Microtubule plus-end binding; microtubule binding. It is involved in the biological process described with: spindle assembly; regulation of microtubule polymerization or depolymerization; protein localization to microtubule plus-end; protein localization to microtubule.
   
   0.726
nis
LP24076p.
   
 
 0.714
CG12861
AT13777p.
   
    0.694
S-Lap7
Sperm-Leucylaminopeptidase 7, isoform A; Manganese ion binding; metalloexopeptidase activity; aminopeptidase activity. It is involved in the biological process described with: proteolysis; multicellular organism reproduction.
  
    0.694
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.