STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DciDodecenoyl-CoA delta-isomerase (Dci) encodes a protein that, when overexpressed, extends lifespan, enhances stress tolerance to oxidative and starvation stress and activates the product of foxo. (262 aa)    
Predicted Functional Partners:
CG4594
LD18769p; enoyl-CoA hydratase activity; dodecenoyl-CoA delta-isomerase activity. It is involved in the biological process described with: fatty acid beta-oxidation.
  
 0.989
CG4592
FI09311p; dodecenoyl-CoA delta-isomerase activity; enoyl-CoA hydratase activity. It is involved in the biological process described with: fatty acid beta-oxidation.
  
 0.987
CG4598
RH73277p; enoyl-CoA hydratase activity; dodecenoyl-CoA delta-isomerase activity. It is involved in the biological process described with: fatty acid beta-oxidation.
  
 0.967
Mfe2
Peroxisomal Multifunctional enzyme type 2 (Mfe2) encodes a multifunctional protein harboring two separate enzyme activities: 2-enoyl-CoA hydratase 2 and 3-hydroxyacyl-CoA dehydrogenase. They function in the peroxisomal fatty acid breakdown spiral of beta-oxidation utilizing the (R)-isomer of the CoA-containing substrate; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 0.891
ScpX
Sterol carrier protein X-related thiolase; Transferase activity, transferring acyl groups other than amino-acyl groups; phospholipid transporter activity. It is involved in the biological process described with: positive regulation of intracellular cholesterol transport; phospholipid transport; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.819
Acox57D-p
Acyl-coenzyme A oxidase; Flavin adenine dinucleotide binding; acyl-CoA oxidase activity; FAD binding; fatty acid binding. It is involved in the biological process described with: fatty acid beta-oxidation; lipid homeostasis; fatty acid beta-oxidation using acyl-CoA oxidase.
  
 0.804
CG9577
RE22677p; delta3,5-delta2,4-dienoyl-CoA isomerase activity. It is involved in the biological process described with: fatty acid beta-oxidation.
  
0.796
Acox57D-d
Acyl-coenzyme A oxidase; FAD binding; fatty acid binding; acyl-CoA oxidase activity; flavin adenine dinucleotide binding. It is involved in the biological process described with: fatty acid beta-oxidation; lipid homeostasis; fatty acid beta-oxidation using acyl-CoA oxidase.
  
 0.786
CG10194
GH04973p; Hydrolase activity.
   
 
 0.762
CG10672
SD02021p; Carbonyl reductase (NADPH) activity; 3-keto sterol reductase activity; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor.
  
 0.743
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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