STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dpr20Defective proboscis extension response 20; It is involved in the biological process described with: synapse organization; sensory perception of chemical stimulus. (525 aa)    
Predicted Functional Partners:
CG31760
Probable G-protein coupled receptor CG31760; G protein-coupled receptor activity. It is involved in the biological process described with: G protein-coupled receptor signaling pathway.
   
    0.837
DIP-epsilon
Dpr-interacting protein epsilon; It is involved in the biological process described with: synapse organization.
   
 
 0.802
CG13901
FI01407p.
    
 
 0.793
CG42553
LD06737p1.
      
 0.780
CG42554
MIP29328p; It is involved in the biological process described with: autophagy.
      
 0.780
DIP-zeta
Dpr-interacting protein zeta, isoform A; It is involved in the biological process described with: synapse organization.
    
 
0.733
Nmdar1
Glutamate [NMDA] receptor subunit 1; NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors. Plays a role in associative learning and in long-term memory consolidation.
   
 
 0.709
CG14015
RE57134p; Alpha-mannosidase activity.
   
 
 0.708
klg
LD10776p; Klingon (klg) encodes a homophilic cell adhesion molecule that is regulated by Notch signalling. It is involved in long term memory formation and photoreceptor cell commitment.
   
    0.681
CG17349
GH16267p; Hsp90 protein binding; chaperone binding; Hsp70 protein binding; G protein-coupled receptor binding. It is involved in the biological process described with: negative regulation of cell death.
      
 0.678
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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