STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LysSLysozyme S; Unlikely to play an active role in the humoral immune defense. May have a function in the digestion of bacteria in the food; Belongs to the glycosyl hydrolase 22 family. (140 aa)    
Predicted Functional Partners:
LysE
Lysozyme E; Unlikely to play an active role in the humoral immune defense. May have a function in the digestion of bacteria in the food; Belongs to the glycosyl hydrolase 22 family.
  
 
 
0.999
LysP
Lysozyme P; Unlikely to play an active role in the humoral immune defense. May have a function in the digestion of bacteria in the food. Belongs to the glycosyl hydrolase 22 family.
  
 
 
0.906
CG8664
LP09593p.
   
    0.799
Ag5r2
Antigen 5-related 2; It is involved in the biological process described with: multicellular organism reproduction; Belongs to the CRISP family.
   
    0.793
yip7
Yippee interacting protein 7; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
   
    0.750
Jon65Aiv
Jonah 65Aiv; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
   
    0.712
Jon25Bii
Jonah 25Bii, isoform A; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
   
    0.679
epsilonTry
Trypsin epsilon; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
   
    0.638
CG31789
LP09219p.
   
    0.632
imd
Protein immune deficiency; Essential for the imd/NF-kappa-B (Imd) humoral and epithelial immune response to Gram-negative bacteria. Functions as an adapter protein that transduces immunity signals from the activation of pathogen recognition receptors (PRRs) by bacterial infection to the Imd signaling pathway. Binding of diaminopimelic acid-type (DAP-type) bacterial peptidoglycans (PGN) causes multimerization or clustering of PGRP receptors which activate the Imd cascade probably by recruiting imd, Fadd and Dredd to the receptor complex. Once in proximity, Dredd cleaves imd in a Fadd-de [...]
      
 0.628
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (26%) [HD]