STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sturkopfLipid droplet-associated hydrolase; Sturkopf (sturkopf) encodes an evolutionary conserved lipid droplet-associated protein. In the absence of lipid droplets, the protein localizes to the endoplasmic reticulum; Belongs to the AB hydrolase superfamily. LDAH family. (307 aa)    
Predicted Functional Partners:
Jheh3
Epoxide hydrolase; Catalyzes juvenile hormone hydrolysis. Belongs to the peptidase S33 family.
   
   0.780
Ldsdh1
Lipid droplet subset dehydrogenase 1; Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; retinol dehydrogenase activity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 
 0.725
ReepB
Receptor expression-enhancing protein; It is involved in the biological process described with: regulation of intracellular transport; endoplasmic reticulum tubular network organization; endoplasmic reticulum organization.
   
  
 0.697
Jabba
Jabba, isoform C; Jabba (Jabba) encodes a lipid droplet protein that sequesters histones on lipid droplets. It promotes proper development of pre-cellular embryos, controls levels of nuclear histones, and mediates anti-bacterial protection.
    
 
 0.681
CG17292
GH01208p; Carboxylic ester hydrolase activity; lipase activity. It is involved in the biological process described with: lipid catabolic process.
   
  
 0.670
puml
RE40534p; Carboxylic ester hydrolase activity; lysophosphatidic acid acyltransferase activity; epoxide hydrolase activity. It is involved in the biological process described with: phosphatidic acid biosynthetic process; lipid homeostasis.
      
 0.668
Mbs
Myosin binding subunit (Mbs) encodes a regulatory subunit of myosin phosphatase. It interacts with the catalytic subunit of the myosin phosphatase encoded by flw. It is involved in cell movement in various biological processes and in the arrest of constriction of contractile rings and ring canals during oogenesis.
    
   0.667
CG34002
SCP domain-containing protein; It is involved in the biological process described with: multicellular organism reproduction.
      
 0.600
Lsd-2
Lipid storage droplet-2 (Lsd-2) encodes a protein associated with lipid droplets. It acts as a barrier for lipases (such as the product of bmm) and thus prevents the mobilization of lipid stores. It is involved in regulation of lipid storage amount and energy homeostasis and acts in concert with the product of Lsd-1; Belongs to the perilipin family.
   
 
 0.573
CG7966
Uncharacterized protein; Selenium binding.
   
  
 0.534
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.