STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG12011RE18076p. (528 aa)    
Predicted Functional Partners:
ase
Achaete-scute complex protein T8; Asense (ase) encodes a transcription factor in the achaete-scute complex. It acts together with other proneural genes in nervous system development, which involves N-mediated lateral inhibition. ase is expressed in the CNS type-I neuroblasts and the PNS sensory organ precursors (SOPs) but not in the proneural clusters that give rise to the SOP via lateral inhibition.
   
  
 0.850
CG10591
Uncharacterized protein.
   
    0.583
CG14110
RE54320p.
   
    0.569
CG13627
Uncharacterized protein, isoform A; Histone methyltransferase activity (H3-K79 specific). It is involved in the biological process described with: histone H3-K79 methylation; regulation of cell cycle.
   
  
 0.497
TwdlN
FI07246p; Structural constituent of chitin-based cuticle. It is involved in the biological process described with: chitin-based cuticle development; body morphogenesis.
   
  
 0.495
TwdlW
LD21452p; Structural constituent of chitin-based cuticle. It is involved in the biological process described with: body morphogenesis; chitin-based cuticle development.
      
 0.469
didum
Dilute class unconventional myosin (didum) encodes a class V unconventional myosin that binds actin and hydrolyzes ATP. It functions in mRNA localization in the oocyte, spermatid individualization during spermatogenesis, transport of pigment granules in photoreceptors and mitochondrial transport in neuronal cells; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
      
 0.435
CG9184
Uncharacterized protein, isoform A.
   
    0.412
CG7888
Uncharacterized protein, isoform B; Amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport.
      
 0.400
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.