STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG12020J domain-containing protein; Chaperone binding; unfolded protein binding. It is involved in the biological process described with: chaperone cofactor-dependent protein refolding. (366 aa)    
Predicted Functional Partners:
CG13442
FI20425p1; Ubiquitin protein ligase activity; ubiquitin-protein transferase activity; zinc ion binding. It is involved in the biological process described with: protein ubiquitination; protein polyubiquitination.
   
  
 0.918
CG17377
Uncharacterized protein, isoform E.
   
  
 0.917
CG31068
MIP03684p.
   
  
 0.909
Rsph3
GH13213p.
   
 
 0.855
CG1077
MIP10102p; It is involved in the biological process described with: chorion-containing eggshell formation; multicellular organism development; cell differentiation.
      
 0.836
Sil1
Nucleotide exchange factor Sil1; Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for an ER lumenal chaperone of HSP70 family (By similarity). Belongs to the SIL1 family.
   
 
 0.751
Hsc70Cb
Hsc70Cb, isoform G; Hsc70Cb (Hsc70Cb) encodes an HSP110 family protein that interacts physically with the product of DnaJ-1 as a chaperone of misfolded proteins. It functions together with the product of DnaJ-1 to prevent the toxicity of aggregation-prone proteins.
  
 
 0.729
CG8336
GH06403p; Peptidyl-prolyl cis-trans isomerase activity; cyclosporin A binding. It is involved in the biological process described with: protein peptidyl-prolyl isomerization; protein folding.
  
 
 0.727
Rsph1
AT19426p; It is involved in the biological process described with: axoneme assembly.
   
 
 0.727
Moca-cyp
Moca-cyp, isoform A; Moca-cyp (Moca-cyp) encodes a peptidyl-prolyl cis-trans isomerase.
  
 
 0.727
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.