Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CG13930WD_REPEATS_REGION domain-containing protein; Dynein heavy chain binding; dynein light chain binding. It is involved in the biological process described with: microtubule-based movement; cilium movement. (685 aa)    
Predicted Functional Partners:
robl
Roadblock (robl) encodes a dynein-associated protein involved in intracellular transport mediated by Dynein. It contributes to dendrite morphogenesis and mushroom body development.
    
 0.948
CG8800
Uncharacterized protein; Motor activity; alpha-tubulin binding; dynein heavy chain binding. It is involved in the biological process described with: outer dynein arm assembly.
    
 0.926
kl-3
Male fertility factor kl3 (kl-3) encodes a dynein heavy chain that is a component of a microtubule motor complex. This motor activity is essential only for spermatogenesis. Lack of kl-3 results in loss of the axonemal out dynein arms in the spermatid tail.
    
 0.921
kl-5
Male fertility factor kl5; ATP binding; microtubule motor activity. It is involved in the biological process described with: microtubule-based movement.
    
 0.920
Dnali1
Putative inner dynein arm light chain, axonemal; May play a dynamic role in flagellar motility.
    
 0.911
Dic61B
Dynein intermediate chain at 61B (Dic61B) encodes an axonemal dynein intermediate chain protein expressed specifically in male germ cells. It is required for the development and precise assembly of sperm axonemes, thus it is essential for male fertility.
  
  
0.910
Dhc93AB
Dynein heavy chain at 93AB (Dhc93AB) encodes a motor protein involved in hearing.
   
 0.861
CG34124
FI23230p1; It is involved in the biological process described with: cilium assembly; cilium-dependent cell motility; sperm axoneme assembly.
    
 
 0.853
CG3339
Uncharacterized protein; Dynein intermediate chain binding; ATP-dependent microtubule motor activity, minus-end-directed; dynein light intermediate chain binding; ATP binding. It is involved in the biological process described with: cilium movement; microtubule-based movement.
   
 0.845
CG9313
Uncharacterized protein, isoform B; Dynein light chain binding; dynein heavy chain binding. It is involved in the biological process described with: cilium movement; outer dynein arm assembly; microtubule-based movement; sensory perception of sound.
  
  
0.821
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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