Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AttA | Def | FBpp0086567 | FBpp0087518 | Attacin-A (AttA) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body and various epithelia under the regulation of the immune deficiency and, to a lesser extent, Toll pathways; Belongs to the attacin/sarcotoxin-2 family. | Defensin (Def) encodes an antibacterial peptide with activity against Gram-positive bacteria. It is induced in the fat body during the systemic immune response and is expressed in various epithelia. The expression of Def is regulated at the transcriptional level by both the immune deficiency and Toll pathways; Belongs to the invertebrate defensin family. Type 1 subfamily. | 0.916 |
| AttA | Dif | FBpp0086567 | FBpp0290792 | Attacin-A (AttA) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body and various epithelia under the regulation of the immune deficiency and, to a lesser extent, Toll pathways; Belongs to the attacin/sarcotoxin-2 family. | Dorsal-related immunity factor Dif; Mediates an immune response in larvae. DIF binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of the immunity gene CECA1. Involved in the melanization immune response to bacterial challenge, possibly by acting in a Toll signaling pathway that downregulates Spn27A in response to infection. Part of a signaling pathway involving NF-kappa-B (rel) and Toll-related receptors, that functions in the apoptosis of unfit cells during cell competition. May be part of a NF-kappa-B and Tollo signaling cascade that regulates dev [...] | 0.609 |
| AttA | DptB | FBpp0086567 | FBpp0085803 | Attacin-A (AttA) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body and various epithelia under the regulation of the immune deficiency and, to a lesser extent, Toll pathways; Belongs to the attacin/sarcotoxin-2 family. | Diptericin B (DptB) encodes an immune inducible antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia. Its expression is regulated at the transcriptional level by the immune deficiency pathway. | 0.999 |
| AttA | Drs | FBpp0086567 | FBpp0072935 | Attacin-A (AttA) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body and various epithelia under the regulation of the immune deficiency and, to a lesser extent, Toll pathways; Belongs to the attacin/sarcotoxin-2 family. | Drosomycin; Possesses antifungal activity and is active against a relatively broad spectrum of filamentous fungi. It inhibits spore germination at high concentrations and at low concentrations delays growth of hyphae which subsequently exhibit abnormal morphology. Spz C-106 in the hemolymph controls expression of the antifungal peptide by acting as a ligand of Tl and inducing an intracellular signaling pathway. Part of a psh-dependent Toll pathway, which may function in activating the systematic immune response in response to localized melanization of the tracheal system. | 0.532 |
| AttA | Mtk | FBpp0086567 | FBpp0086518 | Attacin-A (AttA) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body and various epithelia under the regulation of the immune deficiency and, to a lesser extent, Toll pathways; Belongs to the attacin/sarcotoxin-2 family. | Metchnikowin (Mtk) encodes an antifungal peptide that is secreted from the fat body during the systemic immune response, and is produced by various epithelia. Its expression is regulated at the transcriptional level by the immune deficiency and/or Toll pathways. | 0.991 |
| BG642312 | Drs | FBpp0110067 | FBpp0072935 | BG642312, isoform A; BG642312 (BG642312) encodes a peptide produced in the male accessory glands and transferred to females during mating. | Drosomycin; Possesses antifungal activity and is active against a relatively broad spectrum of filamentous fungi. It inhibits spore germination at high concentrations and at low concentrations delays growth of hyphae which subsequently exhibit abnormal morphology. Spz C-106 in the hemolymph controls expression of the antifungal peptide by acting as a ligand of Tl and inducing an intracellular signaling pathway. Part of a psh-dependent Toll pathway, which may function in activating the systematic immune response in response to localized melanization of the tracheal system. | 0.497 |
| Bbd | Drs | FBpp0311847 | FBpp0072935 | Uncharacterized protein, isoform A; It is involved in the biological process described with: multicellular organism reproduction. | Drosomycin; Possesses antifungal activity and is active against a relatively broad spectrum of filamentous fungi. It inhibits spore germination at high concentrations and at low concentrations delays growth of hyphae which subsequently exhibit abnormal morphology. Spz C-106 in the hemolymph controls expression of the antifungal peptide by acting as a ligand of Tl and inducing an intracellular signaling pathway. Part of a psh-dependent Toll pathway, which may function in activating the systematic immune response in response to localized melanization of the tracheal system. | 0.569 |
| Bbd | Mtk | FBpp0311847 | FBpp0086518 | Uncharacterized protein, isoform A; It is involved in the biological process described with: multicellular organism reproduction. | Metchnikowin (Mtk) encodes an antifungal peptide that is secreted from the fat body during the systemic immune response, and is produced by various epithelia. Its expression is regulated at the transcriptional level by the immune deficiency and/or Toll pathways. | 0.404 |
| Def | AttA | FBpp0087518 | FBpp0086567 | Defensin (Def) encodes an antibacterial peptide with activity against Gram-positive bacteria. It is induced in the fat body during the systemic immune response and is expressed in various epithelia. The expression of Def is regulated at the transcriptional level by both the immune deficiency and Toll pathways; Belongs to the invertebrate defensin family. Type 1 subfamily. | Attacin-A (AttA) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body and various epithelia under the regulation of the immune deficiency and, to a lesser extent, Toll pathways; Belongs to the attacin/sarcotoxin-2 family. | 0.916 |
| Def | Dif | FBpp0087518 | FBpp0290792 | Defensin (Def) encodes an antibacterial peptide with activity against Gram-positive bacteria. It is induced in the fat body during the systemic immune response and is expressed in various epithelia. The expression of Def is regulated at the transcriptional level by both the immune deficiency and Toll pathways; Belongs to the invertebrate defensin family. Type 1 subfamily. | Dorsal-related immunity factor Dif; Mediates an immune response in larvae. DIF binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of the immunity gene CECA1. Involved in the melanization immune response to bacterial challenge, possibly by acting in a Toll signaling pathway that downregulates Spn27A in response to infection. Part of a signaling pathway involving NF-kappa-B (rel) and Toll-related receptors, that functions in the apoptosis of unfit cells during cell competition. May be part of a NF-kappa-B and Tollo signaling cascade that regulates dev [...] | 0.965 |
| Def | DptB | FBpp0087518 | FBpp0085803 | Defensin (Def) encodes an antibacterial peptide with activity against Gram-positive bacteria. It is induced in the fat body during the systemic immune response and is expressed in various epithelia. The expression of Def is regulated at the transcriptional level by both the immune deficiency and Toll pathways; Belongs to the invertebrate defensin family. Type 1 subfamily. | Diptericin B (DptB) encodes an immune inducible antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia. Its expression is regulated at the transcriptional level by the immune deficiency pathway. | 0.950 |
| Def | Drs | FBpp0087518 | FBpp0072935 | Defensin (Def) encodes an antibacterial peptide with activity against Gram-positive bacteria. It is induced in the fat body during the systemic immune response and is expressed in various epithelia. The expression of Def is regulated at the transcriptional level by both the immune deficiency and Toll pathways; Belongs to the invertebrate defensin family. Type 1 subfamily. | Drosomycin; Possesses antifungal activity and is active against a relatively broad spectrum of filamentous fungi. It inhibits spore germination at high concentrations and at low concentrations delays growth of hyphae which subsequently exhibit abnormal morphology. Spz C-106 in the hemolymph controls expression of the antifungal peptide by acting as a ligand of Tl and inducing an intracellular signaling pathway. Part of a psh-dependent Toll pathway, which may function in activating the systematic immune response in response to localized melanization of the tracheal system. | 0.660 |
| Def | Mtk | FBpp0087518 | FBpp0086518 | Defensin (Def) encodes an antibacterial peptide with activity against Gram-positive bacteria. It is induced in the fat body during the systemic immune response and is expressed in various epithelia. The expression of Def is regulated at the transcriptional level by both the immune deficiency and Toll pathways; Belongs to the invertebrate defensin family. Type 1 subfamily. | Metchnikowin (Mtk) encodes an antifungal peptide that is secreted from the fat body during the systemic immune response, and is produced by various epithelia. Its expression is regulated at the transcriptional level by the immune deficiency and/or Toll pathways. | 0.936 |
| Def | dl | FBpp0087518 | FBpp0080560 | Defensin (Def) encodes an antibacterial peptide with activity against Gram-positive bacteria. It is induced in the fat body during the systemic immune response and is expressed in various epithelia. The expression of Def is regulated at the transcriptional level by both the immune deficiency and Toll pathways; Belongs to the invertebrate defensin family. Type 1 subfamily. | Embryonic polarity protein dorsal; Embryonic developmental protein. The lateral or ventral identity of a cell depends upon the concentration of this protein in its nucleus during the blastoderm stage. A morphogenetic protein that specifically binds to the kappa B-related consensus sequence 5'- GRGAAAANCC-3', located in the enhancer region of zygotic genes such as Zen, Twist, Snail and Decapentaplegic. Mediates an immune response in larvae. Part of a signaling pathway involving NF- kappa-B and Toll-related receptors, that functions in the apoptosis of unfit cells during cell competition [...] | 0.900 |
| Dif | AttA | FBpp0290792 | FBpp0086567 | Dorsal-related immunity factor Dif; Mediates an immune response in larvae. DIF binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of the immunity gene CECA1. Involved in the melanization immune response to bacterial challenge, possibly by acting in a Toll signaling pathway that downregulates Spn27A in response to infection. Part of a signaling pathway involving NF-kappa-B (rel) and Toll-related receptors, that functions in the apoptosis of unfit cells during cell competition. May be part of a NF-kappa-B and Tollo signaling cascade that regulates dev [...] | Attacin-A (AttA) encodes an antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body and various epithelia under the regulation of the immune deficiency and, to a lesser extent, Toll pathways; Belongs to the attacin/sarcotoxin-2 family. | 0.609 |
| Dif | Def | FBpp0290792 | FBpp0087518 | Dorsal-related immunity factor Dif; Mediates an immune response in larvae. DIF binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of the immunity gene CECA1. Involved in the melanization immune response to bacterial challenge, possibly by acting in a Toll signaling pathway that downregulates Spn27A in response to infection. Part of a signaling pathway involving NF-kappa-B (rel) and Toll-related receptors, that functions in the apoptosis of unfit cells during cell competition. May be part of a NF-kappa-B and Tollo signaling cascade that regulates dev [...] | Defensin (Def) encodes an antibacterial peptide with activity against Gram-positive bacteria. It is induced in the fat body during the systemic immune response and is expressed in various epithelia. The expression of Def is regulated at the transcriptional level by both the immune deficiency and Toll pathways; Belongs to the invertebrate defensin family. Type 1 subfamily. | 0.965 |
| Dif | DptB | FBpp0290792 | FBpp0085803 | Dorsal-related immunity factor Dif; Mediates an immune response in larvae. DIF binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of the immunity gene CECA1. Involved in the melanization immune response to bacterial challenge, possibly by acting in a Toll signaling pathway that downregulates Spn27A in response to infection. Part of a signaling pathway involving NF-kappa-B (rel) and Toll-related receptors, that functions in the apoptosis of unfit cells during cell competition. May be part of a NF-kappa-B and Tollo signaling cascade that regulates dev [...] | Diptericin B (DptB) encodes an immune inducible antibacterial peptide with activity against Gram-negative bacteria. It is expressed in the fat body during the systemic immune response and in various epithelia. Its expression is regulated at the transcriptional level by the immune deficiency pathway. | 0.836 |
| Dif | Drs | FBpp0290792 | FBpp0072935 | Dorsal-related immunity factor Dif; Mediates an immune response in larvae. DIF binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of the immunity gene CECA1. Involved in the melanization immune response to bacterial challenge, possibly by acting in a Toll signaling pathway that downregulates Spn27A in response to infection. Part of a signaling pathway involving NF-kappa-B (rel) and Toll-related receptors, that functions in the apoptosis of unfit cells during cell competition. May be part of a NF-kappa-B and Tollo signaling cascade that regulates dev [...] | Drosomycin; Possesses antifungal activity and is active against a relatively broad spectrum of filamentous fungi. It inhibits spore germination at high concentrations and at low concentrations delays growth of hyphae which subsequently exhibit abnormal morphology. Spz C-106 in the hemolymph controls expression of the antifungal peptide by acting as a ligand of Tl and inducing an intracellular signaling pathway. Part of a psh-dependent Toll pathway, which may function in activating the systematic immune response in response to localized melanization of the tracheal system. | 0.936 |
| Dif | Mtk | FBpp0290792 | FBpp0086518 | Dorsal-related immunity factor Dif; Mediates an immune response in larvae. DIF binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of the immunity gene CECA1. Involved in the melanization immune response to bacterial challenge, possibly by acting in a Toll signaling pathway that downregulates Spn27A in response to infection. Part of a signaling pathway involving NF-kappa-B (rel) and Toll-related receptors, that functions in the apoptosis of unfit cells during cell competition. May be part of a NF-kappa-B and Tollo signaling cascade that regulates dev [...] | Metchnikowin (Mtk) encodes an antifungal peptide that is secreted from the fat body during the systemic immune response, and is produced by various epithelia. Its expression is regulated at the transcriptional level by the immune deficiency and/or Toll pathways. | 0.669 |
| Dif | dl | FBpp0290792 | FBpp0080560 | Dorsal-related immunity factor Dif; Mediates an immune response in larvae. DIF binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of the immunity gene CECA1. Involved in the melanization immune response to bacterial challenge, possibly by acting in a Toll signaling pathway that downregulates Spn27A in response to infection. Part of a signaling pathway involving NF-kappa-B (rel) and Toll-related receptors, that functions in the apoptosis of unfit cells during cell competition. May be part of a NF-kappa-B and Tollo signaling cascade that regulates dev [...] | Embryonic polarity protein dorsal; Embryonic developmental protein. The lateral or ventral identity of a cell depends upon the concentration of this protein in its nucleus during the blastoderm stage. A morphogenetic protein that specifically binds to the kappa B-related consensus sequence 5'- GRGAAAANCC-3', located in the enhancer region of zygotic genes such as Zen, Twist, Snail and Decapentaplegic. Mediates an immune response in larvae. Part of a signaling pathway involving NF- kappa-B and Toll-related receptors, that functions in the apoptosis of unfit cells during cell competition [...] | 0.963 |
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