Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Cht7Chitinase 7 (Cht7) encodes an enzyme involved in cuticle development, ecdysis and wound healing; Belongs to the glycosyl hydrolase 18 family. (1013 aa)    
Predicted Functional Partners:
kkv
Krotzkopf verkehrt (kkv) encodes a membrane-inserted glycosyltransferase family 2 chitin synthase that uses GlcNAc to produce the polysaccharide chitin, which is extruded to the differentiating cuticle and tracheal system (tracheal cuticle, tube diameter regulation and gas filling).
   
 
 0.988
Chs2
Chitin synthase activity. It is involved in the biological process described with: cuticle chitin biosynthetic process.
    
 0.964
Hexo1
Beta-hexosaminidase; Hexosaminidase 1 (Hexo1) encodes a beta-N-acetylglucosaminidase involved in protein deglycosylation and rhodopsin biosynthesis.
    
 0.911
Hexo2
Beta-hexosaminidase; Hexosaminidase 2 (Hexo2) encodes a beta-N-acetylglucosaminidase involved in carbohydrate metabolism.
    
 0.903
Cda4
Chitin deacetylase-like 4; Chitin binding. It is involved in the biological process described with: chitin metabolic process; carbohydrate metabolic process.
   
  
 0.793
Cht5
Chitinase 5 (Cht5) encodes an enzyme involved in the formation of chitin-based extracellular matrix at barrier tissues; Belongs to the glycosyl hydrolase 18 family.
  
 
0.746
Cht2
Probable chitinase 2; Chitin binding; chitinase activity.
  
 
0.735
Cht12
Chitinase 12 (Cht12) encodes an enzyme involved in cuticle development, ecdysis and wound healing; Belongs to the glycosyl hydrolase 18 family.
  
  
0.723
Cht11
Chitinase activity; chitin binding. It is involved in the biological process described with: chitin catabolic process; carbohydrate metabolic process; Belongs to the glycosyl hydrolase 18 family.
  
  
0.717
Cht10
Probable chitinase 10; Chitinase activity; chitin binding. It is involved in the biological process described with: carbohydrate metabolic process; chitin catabolic process.
  
 
0.713
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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