Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CG14971FI19868p1; Transmembrane transporter activity; antiporter activity. It is involved in the biological process described with: UDP-glucose transmembrane transport. (469 aa)    
Predicted Functional Partners:
CG15564
Uncharacterized protein; It is involved in the biological process described with: positive regulation of cytokinesis.
      
 0.819
CG9967
LD01251p.
      
 0.819
nac
GDP-fucose transporter 1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen. Plays a major role in the fucosylation of N-glycans. Functions redundantly with Efr in the O-fucosylation of Notch, positively regulating Notch signaling; Belongs to the TPT transporter family. SLC35C subfamily.
   
  
 0.748
CycJ
Cyclin J (CycJ) encodes a cyclin-dependent protein serine/threonine kinase regulator that contributes to oogenesis and the early embryonic division cycles.
      
 0.743
frc
UDP-sugar transporter UST74c; Involved in the import of UDP-sugars from the cytoplasm into the Golgi lumen; Belongs to the TPT transporter family. SLC35D subfamily.
   
  
 0.740
CG14621
Solute carrier family 35 member E1 homolog; Putative transporter; Belongs to the TPT transporter family. SLC35E subfamily.
      
 0.736
sll
Slalom (sll) encodes the first transporter of 3'-phosphoadenosine 5'-phosphosulfate (PAPS), that transfers PAPS from cytosol into the lumen of Golgi. It contributes to the sulfation of glycans and proteins, the regulation of several signaling pathways (Hh, Wingless) mediated by glycosaminoglycans during patterning and morphogenesis, and the determination of the embryonic dorsal/ventral axis; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
      
 0.733
Papst2
PAPS transporter 2 (Papst2) encodes the second transporter of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) and localizes in the cis-cisterna of the Golgi and the ER. It transfers PAPS from cytosol into the lumen of Golgi and ER. The product of Papst2 contributes to the sulfation of glycans and proteins, and is suggested to regulate several signaling pathways (Hh, Dpp, Wingless) mediated by glycosaminoglycans in development; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
      
 0.662
CARPB
Carbonic anhydrase-related protein B, isoform A; Hydro-lyase activity; carbonate dehydratase activity; zinc ion binding. It is involved in the biological process described with: one-carbon metabolic process; Belongs to the alpha-carbonic anhydrase family.
      
 0.654
CG6325
LD10232p; It is involved in the biological process described with: protein ubiquitination.
   
  
 0.618
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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