STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG1299CLIP domain-containing serine protease; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. CLIP subfamily. (511 aa)    
Predicted Functional Partners:
Impbeta11
Ran GTPase binding. It is involved in the biological process described with: protein import into nucleus.
      
 0.531
Spn28Da
Serpin 28Da; Serine-type endopeptidase inhibitor activity. It is involved in the biological process described with: negative regulation of proteolysis; negative regulation of endopeptidase activity; multicellular organism reproduction; Belongs to the serpin family.
    
 
 0.499
mri
Mrityu, isoform A; Mrityu (mri) encodes a BTB/POZ domain containing protein. Its expression is regulated by the product of klu during retinal apoptosis. mri protein is phosphorylated upon egg activation, and is required for early embryo development and for the normal sensory perception of touch.
      
 0.497
CG8738
Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis.
  
  
0.482
Spn28B
Serpin 28B, isoform A; Serine-type endopeptidase inhibitor activity. It is involved in the biological process described with: negative regulation of proteolysis; negative regulation of endopeptidase activity; multicellular organism reproduction; Belongs to the serpin family.
    
 
 0.457
CG9649
GH19262p; Endopeptidase activity; serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.446
CG14760
Uncharacterized protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
   
0.431
Spn28Dc
Serine protease inhibitor 28Dc; Serine protease inhibitor which is required for pupal viability and plays an essential role in regulating the melanization reaction. Inhibits spontaneous melanization and appears to be involved in the melanization immune response to physical wounding in larvae and adults. Acts by negatively regulating the Hayan-phenoloxidase (PPO1) cascade in the hemolymph and possibly the trachea. May function by controlling the initial release of the activated form of PPO1, phenoloxidase (PO) and thus maintains PO availability for processes such as wound response and p [...]
   
 
 0.419
CG34409
Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
   
0.418
GCS1
Glucosidase 1, isoform B; Mannosyl-oligosaccharide glucosidase activity. It is involved in the biological process described with: protein N-linked glycosylation; oligosaccharide metabolic process.
   
  
 0.413
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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