Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CG1273RE03558p. (1168 aa)    
Predicted Functional Partners:
CG46025
Uncharacterized protein, isoform D.
      
 0.780
CG15365
Uncharacterized protein, isoform B.
    
 
 0.746
Spn100A
Serpin 100A; Serine-type endopeptidase inhibitor activity. It is involved in the biological process described with: negative regulation of endopeptidase activity; multicellular organism reproduction; Belongs to the serpin family.
   
  
 0.702
CG10864
Uncharacterized protein; Potassium ion leak channel activity; potassium channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; stabilization of membrane potential; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
  
 0.663
CG10082
Kinase activity; inositol hexakisphosphate kinase activity. It is involved in the biological process described with: phosphatidylinositol phosphorylation; inositol phosphate biosynthetic process; Belongs to the inositol phosphokinase (IPK) family.
    
 
 0.655
Coop
Corepressor of Pangolin (Coop) encodes a protein that represses gene expression mediated by Wg signaling. It binds to the product of pan preventing the interaction of the products of pan with arm. By antagonizing Wg signaling, it contributes to patterning and cell fate decisions during development.
      
 0.655
CG11905
LD29172p.
   
    0.653
osy
RE14039p; ATP binding; ATPase activity. It is involved in the biological process described with: transmembrane transport.
      
 0.652
Lnpk
Lunapark, isoform A; It is involved in the biological process described with: endoplasmic reticulum tubular network organization.
      
 0.651
CG4440
GEO09613p1.
   
  
 0.646
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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