STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG18418CG18418 protein; Oxoglutarate:malate antiporter activity. It is involved in the biological process described with: malate transport; mitochondrial transport; alpha-ketoglutarate transport; Belongs to the mitochondrial carrier (TC 2.A.29) family. (311 aa)    
Predicted Functional Partners:
Scsalpha2
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
   
  
 0.883
ND-49L
NADH dehydrogenase activity; quinone binding; NADH dehydrogenase (ubiquinone) activity; NAD binding. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone; Belongs to the complex I 49 kDa subunit family.
   
  
 0.851
CG4983
GH17939p.
   
    0.826
CG10589
GH01788p.
   
    0.816
CG6380
AT25465p; Protein phosphatase inhibitor activity. It is involved in the biological process described with: regulation of phosphoprotein phosphatase activity; regulation of signal transduction.
   
    0.814
sut4
Sugar transporter 4; Carbohydrate:proton symporter activity. It is involved in the biological process described with: glucose import; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
   
    0.810
SdhAL
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
   
 
 0.795
ssp5
Short spindle 5.
   
    0.793
sowi
IP07034p; Calcium ion binding.
   
    0.761
Dic2
Dicarboxylate carrier 2, isoform A; Belongs to the mitochondrial carrier (TC 2.A.29) family.
  
   
0.750
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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