Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CG15211RE01453p. (177 aa)    
Predicted Functional Partners:
tsu
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. Involved in exon definition of genes containing long introns, including the rolled/MAPK gene. The mago-tsu heterodimer interacts with the EJC key regulator Pym leading to EJC disassembly in the cytoplasm. Has a role in oskar mRNA localization to the posterior pole of the developing oocyte. Belongs to the RBM8A family.
    
 
 0.794
Pym
Partner of Y14 and mago; Regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as an EJC disassembly factor by disrupting mature EJC from spliced mRNAs. Required for normal localization of osk mRNA to the posterior pole of the developing oocyte. Does not interact with the small ribosomal unit [...]
    
   0.787
CG15916
RH08992p; It is involved in the biological process described with: rRNA processing.
   
  
 0.655
CG9427
GH19763p; Oxidoreductase activity.
      
 0.642
CG6299
RH52220p; Lipid binding; ceramide 1-phosphate transfer activity; ceramide 1-phosphate binding. It is involved in the biological process described with: intermembrane lipid transfer; ceramide transport.
   
   0.615
Tsp
Thrombospondin, isoform A; Thrombospondin (Tsp) is expressed in embryonic tendons and is regulated by sr. The product of Tsp serves as a ligand for the integrin subunit encoded by if and is required for muscle adhesion to tendons.
   
  
 0.599
CG13559
FI16602p1; It is involved in the biological process described with: positive regulation of hemocyte proliferation.
   
  
 0.597
CG3829
GH19047p; Belongs to the CD36 family.
      
 0.597
CG5027
LD24073p; Thiol oxidase activity. It is involved in the biological process described with: peptidyl-cysteine oxidation; cell redox homeostasis.
      
 0.593
CG31038
Uncharacterized protein, isoform A.
   
  
 0.586
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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