Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Rab9FaRab at 9Fa; GTP binding; GTPase activity. (197 aa)    
Predicted Functional Partners:
betaggt-II
Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. Belongs to the protein prenyltransferase subunit beta family.
    
 0.869
Gdi
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
    
 0.852
Rab11
Rab11, isoform A; Rab11 (Rab11) encodes a Rab type protein. Rab proteins are ubiquitously expressed family of small monomeric Ras-like GTPases that are key regulators of endomembrane traffiking, regulating exocytosis, endocytosis and membrane recycling processes essential for maintaining various cellular functions.
  
0.828
CG5745
LD44506p; Rab GTPase binding; GTPase activator activity. It is involved in the biological process described with: regulation of GTPase activity; intracellular protein transport; activation of GTPase activity.
    
 
 0.784
Bet3
Trafficking protein particle complex subunit; Blocked early in transport 3 (Bet3) encodes a protein involved in dsRNA transport; Belongs to the TRAPP small subunits family. BET3 subfamily.
    
 
 0.781
p115
General vesicular transport factor p115; Essential for maintaining the architecture of the Golgi stacks and for normal organization of the transitional endoplasmic reticulum (tER). Required for both the formation of the Golgi stacks and the maintenance of the individual cisternae. Belongs to the VDP/USO1/EDE1 family.
   
 
 0.776
l(3)76BDm
Lethal (3) 76BDm, isoform A; It is involved in the biological process described with: autophagy of peroxisome; Golgi vesicle transport; endoplasmic reticulum to Golgi vesicle-mediated transport; protein localization to phagophore assembly site; autophagosome assembly.
    
 
 0.771
Syx5
Syntaxin-5; Syntaxin 5 (Syx5) encodes a type II transmembrane protein in the Q-SNARE family that forms hetero tetramers required for membrane function in the early secretory pathway (ER and Golgi). It has been involved in cytokinesis during spermatogenesis.
    
 
 0.768
Slh
Protein sly1 homolog; Non-vital for development.
    
 
 0.751
Bet5
Trafficking protein particle complex subunit; Rab guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: Golgi vesicle transport; vesicle-mediated transport; endoplasmic reticulum to Golgi vesicle-mediated transport; Belongs to the TRAPP small subunits family.
    
 
 0.736
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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