STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG32669Putative sodium-dependent multivitamin transporter; Symporter activity. It is involved in the biological process described with: sodium ion transport; transmembrane transport. (604 aa)    
Predicted Functional Partners:
tomboy40
Mitochondrial import receptor subunit TOM40 homolog 2; Channel-forming protein essential for import of protein precursors into mitochondria; Belongs to the Tom40 family.
      
 0.835
TwdlB
TweedleB; Structural constituent of chitin-based cuticle. It is involved in the biological process described with: body morphogenesis; chitin-based cuticle development.
      
 0.669
CG4701
FI08533p; ATP binding; Belongs to the AAA ATPase family.
      
 0.662
slgA
Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate.
  
  
 0.636
Grx1t
Glutaredoxin 1, testis-specific; Electron transfer activity; protein disulfide oxidoreductase activity; glutathione-disulfide reductase activity. It is involved in the biological process described with: cellular response to oxidative stress; cell redox homeostasis.
      
 0.628
Vha16-2
V-type proton ATPase proteolipid subunit; Vacuolar H[+] ATPase 16kD subunit 2 (Vha16-2) encodes the main subunit of the membrane-embedded V0 sector of the vacuolar-ATPase, which is responsible for acidification of the endo-lysosomal lumen and other cellular compartment. As part of the V-ATPase, the product of Vha16-2 supports membrane trafficking, protein degradation and multiple associated signaling pathways, such as mTor, Wnt and Notch.
      
 0.609
Pp1-87B
Serine/threonine-protein phosphatase alpha-2 isoform; Is essential for the regulation of mitotic chromosomal segregation as well as regulation of chromatin condensation during interphase; Belongs to the PPP phosphatase family. PP-1 subfamily.
      
 0.606
Twdlbeta
Tweedlebeta; Structural constituent of chitin-based cuticle. It is involved in the biological process described with: chitin-based cuticle development; body morphogenesis.
      
 0.601
P5CS
Delta-1-pyrroline-5-carboxylate synthase; Glutamate-5-semialdehyde dehydrogenase activity; glutamate 5-kinase activity; delta1-pyrroline-5-carboxylate synthetase activity. It is involved in the biological process described with: oxidation-reduction process; proline biosynthetic process; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
     
 0.572
CG9582
AT23224p; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.533
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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