Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG32320 | rho-4 | FBpp0308933 | FBpp0073365 | DC_STAMP domain-containing protein. | Rhomboid-4, isoform A; Rhomboid-4 (rho-4) encodes a member of the rhomboid superfamily of intramembrane serine proteases, which cleave to release proteins from the membrane. It processes the transmembrane EGF ligands encoded by spi, Krn, and grk. Its activity is directly and dramatically stimulated by calcium; Belongs to the peptidase S54 family. | 0.495 |
| Krn | rho-4 | FBpp0074961 | FBpp0073365 | LD34429p; Keren (Krn) encodes an ligand for the receptor encoded by Egfr that is processed by the products of S and rho. It shows a redundant role with the products of spi in very few tissues. | Rhomboid-4, isoform A; Rhomboid-4 (rho-4) encodes a member of the rhomboid superfamily of intramembrane serine proteases, which cleave to release proteins from the membrane. It processes the transmembrane EGF ligands encoded by spi, Krn, and grk. Its activity is directly and dramatically stimulated by calcium; Belongs to the peptidase S54 family. | 0.469 |
| Pmm2 | rho-4 | FBpp0075693 | FBpp0073365 | Probable phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. | Rhomboid-4, isoform A; Rhomboid-4 (rho-4) encodes a member of the rhomboid superfamily of intramembrane serine proteases, which cleave to release proteins from the membrane. It processes the transmembrane EGF ligands encoded by spi, Krn, and grk. Its activity is directly and dramatically stimulated by calcium; Belongs to the peptidase S54 family. | 0.499 |
| Rho1 | RhoGAP92B | FBpp0086354 | FBpp0310730 | Ras-like GTP-binding protein Rho1; Has a role in regulating actin cytoskeletal organization: required during early development for proper execution of morphogenetic movements of individual cells and groups of cells important for the formation of the embryonic body plan. Plays a role in regulating dorsal closure during embryogenesis. During axis elongation, required for Rho-kinase Rok planar polarity and adherens junction localization as well as for generating a planar polarized distribution of the actin-binding protein Shrm. During embryogenesis, acts upstream of wash to regulate the d [...] | Rho GTPase-activating protein 92B; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.492 |
| Rho1 | Sema1b | FBpp0086354 | FBpp0086050 | Ras-like GTP-binding protein Rho1; Has a role in regulating actin cytoskeletal organization: required during early development for proper execution of morphogenetic movements of individual cells and groups of cells important for the formation of the embryonic body plan. Plays a role in regulating dorsal closure during embryogenesis. During axis elongation, required for Rho-kinase Rok planar polarity and adherens junction localization as well as for generating a planar polarized distribution of the actin-binding protein Shrm. During embryogenesis, acts upstream of wash to regulate the d [...] | Chemorepellent activity; semaphorin receptor binding; Belongs to the semaphorin family. | 0.534 |
| Rho1 | rho-4 | FBpp0086354 | FBpp0073365 | Ras-like GTP-binding protein Rho1; Has a role in regulating actin cytoskeletal organization: required during early development for proper execution of morphogenetic movements of individual cells and groups of cells important for the formation of the embryonic body plan. Plays a role in regulating dorsal closure during embryogenesis. During axis elongation, required for Rho-kinase Rok planar polarity and adherens junction localization as well as for generating a planar polarized distribution of the actin-binding protein Shrm. During embryogenesis, acts upstream of wash to regulate the d [...] | Rhomboid-4, isoform A; Rhomboid-4 (rho-4) encodes a member of the rhomboid superfamily of intramembrane serine proteases, which cleave to release proteins from the membrane. It processes the transmembrane EGF ligands encoded by spi, Krn, and grk. Its activity is directly and dramatically stimulated by calcium; Belongs to the peptidase S54 family. | 0.435 |
| Rho1 | spi | FBpp0086354 | FBpp0080809 | Ras-like GTP-binding protein Rho1; Has a role in regulating actin cytoskeletal organization: required during early development for proper execution of morphogenetic movements of individual cells and groups of cells important for the formation of the embryonic body plan. Plays a role in regulating dorsal closure during embryogenesis. During axis elongation, required for Rho-kinase Rok planar polarity and adherens junction localization as well as for generating a planar polarized distribution of the actin-binding protein Shrm. During embryogenesis, acts upstream of wash to regulate the d [...] | Protein spitz; Ligand for the EGF receptor (Gurken). Involved in a number of unrelated developmental choices, for example, dorsal-ventral axis formation, glial migration, sensory organ determination, and muscle development. It is required for photoreceptor determination. | 0.492 |
| RhoGAP92B | Rho1 | FBpp0310730 | FBpp0086354 | Rho GTPase-activating protein 92B; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | Ras-like GTP-binding protein Rho1; Has a role in regulating actin cytoskeletal organization: required during early development for proper execution of morphogenetic movements of individual cells and groups of cells important for the formation of the embryonic body plan. Plays a role in regulating dorsal closure during embryogenesis. During axis elongation, required for Rho-kinase Rok planar polarity and adherens junction localization as well as for generating a planar polarized distribution of the actin-binding protein Shrm. During embryogenesis, acts upstream of wash to regulate the d [...] | 0.492 |
| RhoGAP92B | Sema1b | FBpp0310730 | FBpp0086050 | Rho GTPase-activating protein 92B; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | Chemorepellent activity; semaphorin receptor binding; Belongs to the semaphorin family. | 0.442 |
| RhoGAP92B | rho-4 | FBpp0310730 | FBpp0073365 | Rho GTPase-activating protein 92B; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | Rhomboid-4, isoform A; Rhomboid-4 (rho-4) encodes a member of the rhomboid superfamily of intramembrane serine proteases, which cleave to release proteins from the membrane. It processes the transmembrane EGF ligands encoded by spi, Krn, and grk. Its activity is directly and dramatically stimulated by calcium; Belongs to the peptidase S54 family. | 0.521 |
| S2P | rho-4 | FBpp0087169 | FBpp0073365 | Metalloendopeptidase activity. It is involved in the biological process described with: positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress; sterol regulatory element binding protein cleavage; membrane protein intracellular domain proteolysis; positive regulation of DNA-binding transcription factor activity. | Rhomboid-4, isoform A; Rhomboid-4 (rho-4) encodes a member of the rhomboid superfamily of intramembrane serine proteases, which cleave to release proteins from the membrane. It processes the transmembrane EGF ligands encoded by spi, Krn, and grk. Its activity is directly and dramatically stimulated by calcium; Belongs to the peptidase S54 family. | 0.437 |
| Scp2 | rho-4 | FBpp0082806 | FBpp0073365 | Cex Ca2+-sensing low molecular weight GTPase; GTPase activity; calcium ion binding. | Rhomboid-4, isoform A; Rhomboid-4 (rho-4) encodes a member of the rhomboid superfamily of intramembrane serine proteases, which cleave to release proteins from the membrane. It processes the transmembrane EGF ligands encoded by spi, Krn, and grk. Its activity is directly and dramatically stimulated by calcium; Belongs to the peptidase S54 family. | 0.422 |
| Sema1b | Rho1 | FBpp0086050 | FBpp0086354 | Chemorepellent activity; semaphorin receptor binding; Belongs to the semaphorin family. | Ras-like GTP-binding protein Rho1; Has a role in regulating actin cytoskeletal organization: required during early development for proper execution of morphogenetic movements of individual cells and groups of cells important for the formation of the embryonic body plan. Plays a role in regulating dorsal closure during embryogenesis. During axis elongation, required for Rho-kinase Rok planar polarity and adherens junction localization as well as for generating a planar polarized distribution of the actin-binding protein Shrm. During embryogenesis, acts upstream of wash to regulate the d [...] | 0.534 |
| Sema1b | RhoGAP92B | FBpp0086050 | FBpp0310730 | Chemorepellent activity; semaphorin receptor binding; Belongs to the semaphorin family. | Rho GTPase-activating protein 92B; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.442 |
| Sema1b | rho-4 | FBpp0086050 | FBpp0073365 | Chemorepellent activity; semaphorin receptor binding; Belongs to the semaphorin family. | Rhomboid-4, isoform A; Rhomboid-4 (rho-4) encodes a member of the rhomboid superfamily of intramembrane serine proteases, which cleave to release proteins from the membrane. It processes the transmembrane EGF ligands encoded by spi, Krn, and grk. Its activity is directly and dramatically stimulated by calcium; Belongs to the peptidase S54 family. | 0.435 |
| grk | rho-4 | FBpp0079313 | FBpp0073365 | Protein gurken; Critical for defining the anterior-posterior and dorsal- ventral axes of the egg. May signal directly to dorsal follicle cells through the receptor torpedo (top). During oogenesis this signaling pathway instructs follicle cells to follow a dorsal pathway of development rather than the default ventral pathway. | Rhomboid-4, isoform A; Rhomboid-4 (rho-4) encodes a member of the rhomboid superfamily of intramembrane serine proteases, which cleave to release proteins from the membrane. It processes the transmembrane EGF ligands encoded by spi, Krn, and grk. Its activity is directly and dramatically stimulated by calcium; Belongs to the peptidase S54 family. | 0.674 |
| rho-4 | CG32320 | FBpp0073365 | FBpp0308933 | Rhomboid-4, isoform A; Rhomboid-4 (rho-4) encodes a member of the rhomboid superfamily of intramembrane serine proteases, which cleave to release proteins from the membrane. It processes the transmembrane EGF ligands encoded by spi, Krn, and grk. Its activity is directly and dramatically stimulated by calcium; Belongs to the peptidase S54 family. | DC_STAMP domain-containing protein. | 0.495 |
| rho-4 | Krn | FBpp0073365 | FBpp0074961 | Rhomboid-4, isoform A; Rhomboid-4 (rho-4) encodes a member of the rhomboid superfamily of intramembrane serine proteases, which cleave to release proteins from the membrane. It processes the transmembrane EGF ligands encoded by spi, Krn, and grk. Its activity is directly and dramatically stimulated by calcium; Belongs to the peptidase S54 family. | LD34429p; Keren (Krn) encodes an ligand for the receptor encoded by Egfr that is processed by the products of S and rho. It shows a redundant role with the products of spi in very few tissues. | 0.469 |
| rho-4 | Pmm2 | FBpp0073365 | FBpp0075693 | Rhomboid-4, isoform A; Rhomboid-4 (rho-4) encodes a member of the rhomboid superfamily of intramembrane serine proteases, which cleave to release proteins from the membrane. It processes the transmembrane EGF ligands encoded by spi, Krn, and grk. Its activity is directly and dramatically stimulated by calcium; Belongs to the peptidase S54 family. | Probable phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. | 0.499 |
| rho-4 | Rho1 | FBpp0073365 | FBpp0086354 | Rhomboid-4, isoform A; Rhomboid-4 (rho-4) encodes a member of the rhomboid superfamily of intramembrane serine proteases, which cleave to release proteins from the membrane. It processes the transmembrane EGF ligands encoded by spi, Krn, and grk. Its activity is directly and dramatically stimulated by calcium; Belongs to the peptidase S54 family. | Ras-like GTP-binding protein Rho1; Has a role in regulating actin cytoskeletal organization: required during early development for proper execution of morphogenetic movements of individual cells and groups of cells important for the formation of the embryonic body plan. Plays a role in regulating dorsal closure during embryogenesis. During axis elongation, required for Rho-kinase Rok planar polarity and adherens junction localization as well as for generating a planar polarized distribution of the actin-binding protein Shrm. During embryogenesis, acts upstream of wash to regulate the d [...] | 0.435 |
page 1 of 2