STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG2533Uncharacterized protein. (180 aa)    
Predicted Functional Partners:
CG14448
AT10852p.
   
    0.750
CG17717
Uncharacterized protein, isoform A; Ubiquitin protein ligase activity; ubiquitin-protein transferase activity; zinc ion binding. It is involved in the biological process described with: protein ubiquitination.
   
    0.692
CG6470
GH25257p; Nucleic acid binding.
   
    0.681
fzr2
Fizzy-related 2 (fzr2) is exclusively expressed in testis and encodes a protein that binds to the anaphase-promoting complex/cyclosome (APC/C). As for the related proteins encoded by fzr, fzy and cort, it activates the ubiquitin ligase activity of the APC/C and allows the recruitment of target proteins such as those encoded by CycA, CycB, CycB3 and pim.
   
    0.679
CG15638
GEO12036p1.
   
    0.675
CG4681
FI06118p.
   
    0.641
CG8584
AT02326p; Protein serine/threonine phosphatase activity; phosphoprotein phosphatase activity. It is involved in the biological process described with: protein dephosphorylation.
   
    0.629
UQCR-14L
Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family.
   
    0.567
CG17217
GEO12039p1.
   
    0.565
CG17764
Uncharacterized protein; It is involved in the biological process described with: mRNA splicing, via spliceosome.
   
    0.562
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.