STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG10362LD34222p; Lipid binding. It is involved in the biological process described with: intracellular signal transduction; mitochondrial calcium ion homeostasis; mitochondrion-endoplasmic reticulum membrane tethering. (1037 aa)    
Predicted Functional Partners:
CG43783
Uncharacterized protein, isoform G; Lipid binding.
   
  
 0.593
Vmat
Vesicular monoamine transporter (Vmat) encodes a protein responsible for packaging the neurotransmitters dopamine, serotonin and octopamine into secretory vesicles.
   
  
 0.544
CG13887
LP10861p; It is involved in the biological process described with: endoplasmic reticulum to Golgi vesicle-mediated transport; protein localization to endoplasmic reticulum exit site; intracellular protein transport.
      
 0.531
CG15270
Anoctamin; Intracellular calcium activated chloride channel activity; calcium activated cation channel activity. It is involved in the biological process described with: chloride transport; cation transport; transmembrane transport.
   
    0.530
KrT95D
Krueppel target at 95D, isoform A; It is involved in the biological process described with: protein localization to plasma membrane.
      
 0.525
Lnpk
Lunapark, isoform A; It is involved in the biological process described with: endoplasmic reticulum tubular network organization.
    
 
 0.504
Aplip1
JNK-interacting protein 1; The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity).
   
    0.497
CG4341
Protein O-mannosyl-transferase TMTC2; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues.
   
    0.483
Vps13
Vacuolar protein sorting-associated protein 13; Plays a role in the survival of neurons by maintaining protein homeostasis in the central nervous system. May function as part of a lysosomal degradation pathway.
      
 0.433
CG8814
LD25952p; fatty-acyl-CoA binding.
      
 0.428
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.