STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
p24-1P24-related-1, isoform A; P24-related-1 (p24-1) encodes a p24 protein that contributes to the secretion of Wnt ligands. (210 aa)    
Predicted Functional Partners:
bai
Transmembrane emp24 domain-containing protein bai; Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected; Belongs to the EMP24/GP25L family.
   
0.982
CHOp24
CHOp24, isoform A; CHOp24 (CHOp24) encodes a p24 transporter that contributes to the intracellular trafficking between the ER and Golgi. It is required for secretion of Wnt ligands.
   
0.954
eca
Transmembrane emp24 domain-containing protein eca; Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected. Involved in Golgi organization. Belongs to the EMP24/GP25L family.
   
0.932
p24-2
P24-related-2, isoform A; P24-related-2 (p24-2) encodes a p24-transporter-type protein involved in post-mating oviposition.
   
0.919
mRpL46
Mitochondrial ribosomal protein L46; Structural constituent of ribosome; hydrolase activity. It is involved in the biological process described with: mitochondrial translation.
   
 
 0.918
Traf6
TNF-receptor-associated factor 6 (Traf6) encodes a protein that belongs to a family of adaptor proteins involved in transducing downstream signaling by interacting with cell surface receptors. It mediates the pro-inflammatory effects of Toll and related receptor signaling, and the cell death induced by JNK activation via the product of egr.
   
 
 0.916
mRpS35
Mitochondrial ribosomal protein S35; Structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; translation.
   
 
 0.915
mRpL16
Mitochondrial ribosomal protein L16, isoform A; Structural constituent of ribosome; rRNA binding. It is involved in the biological process described with: mitochondrial translation.
   
   0.910
mRpL15
Mitochondrial ribosomal protein L15; Structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation.
   
   0.909
mRpS29
Mitochondrial ribosomal protein S29; Structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; apoptotic process; translation.
   
 
 0.906
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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