STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cpr11ACuticular protein 11A; Structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development. (270 aa)    
Predicted Functional Partners:
CG17349
GH16267p; Hsp90 protein binding; chaperone binding; Hsp70 protein binding; G protein-coupled receptor binding. It is involved in the biological process described with: negative regulation of cell death.
    
 
 0.854
CG42258
Uncharacterized protein, isoform C.
      
 0.836
CG17350
IP12334p.
      
 0.835
PH4alphaNE2
Prolyl-4-hydroxylase-alpha NE2; Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; L-ascorbic acid binding; iron ion binding; procollagen-proline 4-dioxygenase activity. It is involved in the biological process described with: oxidation-reduction process; peptidyl-proline hydroxylation to 4-hydroxy-L-proline; cell migration; multicellular organism reproduction.
    
 
 0.689
CG2556
RE14150p.
   
 
 0.687
TwdlD
RE49895p; TweedleD (TwdlD) encodes a chitin-binding protein that is a member of the Tweedle family of cuticle proteins.
   
  
 0.682
Cpr62Bb
Cuticular protein 62Bb, isoform A; Structural constituent of cuticle; structural constituent of chitin-based larval cuticle. It is involved in the biological process described with: chitin-based cuticle development.
   
 
 0.669
dpr20
Defective proboscis extension response 20; It is involved in the biological process described with: synapse organization; sensory perception of chemical stimulus.
    
 
 0.632
Cpr65Ec
Cuticular protein 65Ec; Structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development.
   
  
 0.631
CG13705
RE67967p.
   
   0.595
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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