STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG11085IP01054p; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; animal organ development. (295 aa)    
Predicted Functional Partners:
CG12523
RE74758p.
   
 
 0.911
CG14431
MIP31509p.
   
  
 0.856
ms(2)34Fe
Male sterile (2) 34Fe; It is involved in the biological process described with: spermatid differentiation.
   
  
 0.839
CG16868
VWFA and cache domain-containing protein CG16868; Voltage-gated calcium channel activity.
      
 0.793
Rbp6
RNA-binding protein 6 (Rbp6) encodes a paralog of the RNA-binding protein encoded by msi. In contrast to msi, Rbp6 mutants are viable and fertile, with only a slight delay in eclosion. The product of Rbp6 may have roles in response to fungal infection and aggressive behavior.
      
 0.668
CG10864
Uncharacterized protein; Potassium ion leak channel activity; potassium channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; stabilization of membrane potential; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
    0.620
RpL23
60S ribosomal protein L23; Large ribosomal subunit rRNA binding; structural constituent of ribosome; myosin binding. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the universal ribosomal protein uL14 family.
      
 0.601
CG13634
Uncharacterized protein.
   
    0.592
CG12849
Uncharacterized protein.
   
    0.577
CG9109
Uncharacterized protein, isoform C; Acetylglucosaminyltransferase activity.
   
    0.561
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: medium (70%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.