FI07430p; Histone deacetylase activity; histone deacetylase binding. It is involved in the biological process described with: histone deacetylation; negative regulation of transcription by RNA polymerase II.

Histone deacetylase complex subunit SAP30 homolog; Component of the class 1 Sin3A-histone deacetylase (Rpd3) complex (HDAC). Appears to be a non-essential subunit of this complex which is not required for cell cycle regulation of progression through the G2 phase of the cell cycle; Belongs to the SAP30 family.

Histone deacetylase HDAC1; Catalyzes the deacetylation of lysine residues on the N- terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation may constitute a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. For instance, deacetylation of histone H3 may be a prerequisite for the subsequent recruitment of the histone methyltransferase Su(var)3-9 to histones. Involved in position-effect variegation (PEV). In the larval brain, part of a regulatory network including the transcript [...]

Inhibitor of growth protein; Methylated histone binding. It is involved in the biological process described with: positive regulation of transcription, DNA-templated.

Probable histone-binding protein Caf1; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the nucleosome remodeling and deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylati [...]

GH06635p; Transcription coregulator activity. It is involved in the biological process described with: negative regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated.

FI15207p1; It is involved in the biological process described with: regulation of transcription, DNA-templated.

Sin3A-associated protein 130, isoform C; It is involved in the biological process described with: negative regulation of transcription by RNA polymerase II.

Hat-trick, isoform D; Transcription regulatory region sequence-specific DNA binding; chromatin binding; transcription cofactor binding; DNA-binding transcription factor binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; negative regulation of neuron death; positive regulation of Notch signaling pathway.