STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG42237Uncharacterized protein, isoform A; Calcium-dependent phospholipase A2 activity. It is involved in the biological process described with: arachidonic acid secretion; phospholipid metabolic process. (363 aa)    
Predicted Functional Partners:
CG13014
RE09848p.
      
 0.836
CG30274
Uncharacterized protein; Creatine kinase activity; kinase activity. It is involved in the biological process described with: phosphocreatine biosynthetic process; Belongs to the ATP:guanido phosphotransferase family.
    
 
 0.816
RpL21
Ribosomal protein L21, isoform A; Structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation.
   
 
 0.814
CG15916
RH08992p; It is involved in the biological process described with: rRNA processing.
      
 0.790
bcn92
Protein bcn92; It is involved in the biological process described with: iron-sulfur cluster assembly; Belongs to the complex I LYR family.
    
 
 0.726
mt:Cyt-b
Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
   
 
 0.726
RpL13A
Ribosomal protein L13A (RpL13A) encodes a component of the large ribosomal subunit, and thus involved in mRNA translation. Mutations in genes encoding ribosomal proteins affect fertility, viability and other Drosophila phenotypes, described as Minute; Belongs to the universal ribosomal protein uL13 family.
   
 
 0.714
RpL8
Ribosomal protein L8 (RpL8) encodes a ribosomal structural constituent.
   
 
 0.713
mRpL2
Mitochondrial ribosomal protein L2; RNA binding; structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation.
   
 
 0.678
CG9541
Uncharacterized protein, isoform D; Nucleoside diphosphate kinase activity; ATP binding. It is involved in the biological process described with: nucleoside diphosphate phosphorylation; purine nucleotide metabolic process; nucleoside triphosphate biosynthetic process.
      
 0.672
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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