| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG10674 | Fer3HCH | FBpp0076884 | FBpp0073576 | Protein Asterix. | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. | 0.676 |
| CG15200 | Fer3HCH | FBpp0073301 | FBpp0073576 | GEO10752p1; It is involved in the biological process described with: sperm competition. | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. | 0.683 |
| ClC-a | Fer3HCH | FBpp0082002 | FBpp0073576 | Chloride channel protein 2; Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport; Belongs to the chloride channel (TC 2.A.49) family. | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. | 0.699 |
| ClC-a | Trpm | FBpp0082002 | FBpp0308223 | Chloride channel protein 2; Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport; Belongs to the chloride channel (TC 2.A.49) family. | Transient receptor potential cation channel trpm; Calcium channel mediating constitutive calcium ion entry. Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. | 0.815 |
| FeCH | Fer3HCH | FBpp0085208 | FBpp0073576 | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. | 0.918 |
| FeCH | Ho | FBpp0085208 | FBpp0081900 | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. | 0.951 |
| FeCH | Mvl | FBpp0085208 | FBpp0303079 | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | Malvolio (Mvl) encodes a member of the SLC11 family of metal ion transporters that transports divalent metal cations, including Mn[2+] and Fe[2+]. Its function has been linked to feeding-related decisions, possibly via modulation of dopaminergic signaling. | 0.443 |
| FeCH | Roc2 | FBpp0085208 | FBpp0291421 | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | Regulator of cullins 2 (Roc2) encodes a C2H2 type zinc finger protein that binds specifically to the product of Cul5 and recruits ubiquitin-charged E2 to the CRL5 E3 ubiquitin ligase complex, which functions during oogenesis. | 0.416 |
| FeCH | fh | FBpp0085208 | FBpp0071283 | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | Frataxin homolog, mitochondrial; Promotes the biosynthesis of heme as well as the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+). May be able to store large amounts of the metal in the form of a ferrihydrite mineral by oligomerization. Required for ecdysteroidogenesis in the prothoracic gland which is necessary for larval to pupal transition. Belongs to the frataxin family. | 0.993 |
| FeCH | mfrn | FBpp0085208 | FBpp0084635 | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | Mitoferrin; Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.607 |
| Fer3HCH | CG10674 | FBpp0073576 | FBpp0076884 | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. | Protein Asterix. | 0.676 |
| Fer3HCH | CG15200 | FBpp0073576 | FBpp0073301 | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. | GEO10752p1; It is involved in the biological process described with: sperm competition. | 0.683 |
| Fer3HCH | ClC-a | FBpp0073576 | FBpp0082002 | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. | Chloride channel protein 2; Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport; Belongs to the chloride channel (TC 2.A.49) family. | 0.699 |
| Fer3HCH | FeCH | FBpp0073576 | FBpp0085208 | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.918 |
| Fer3HCH | Ho | FBpp0073576 | FBpp0081900 | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. | 0.937 |
| Fer3HCH | Mvl | FBpp0073576 | FBpp0303079 | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. | Malvolio (Mvl) encodes a member of the SLC11 family of metal ion transporters that transports divalent metal cations, including Mn[2+] and Fe[2+]. Its function has been linked to feeding-related decisions, possibly via modulation of dopaminergic signaling. | 0.653 |
| Fer3HCH | Roc2 | FBpp0073576 | FBpp0291421 | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. | Regulator of cullins 2 (Roc2) encodes a C2H2 type zinc finger protein that binds specifically to the product of Cul5 and recruits ubiquitin-charged E2 to the CRL5 E3 ubiquitin ligase complex, which functions during oogenesis. | 0.684 |
| Fer3HCH | Trpm | FBpp0073576 | FBpp0308223 | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. | Transient receptor potential cation channel trpm; Calcium channel mediating constitutive calcium ion entry. Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. | 0.704 |
| Fer3HCH | fh | FBpp0073576 | FBpp0071283 | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. | Frataxin homolog, mitochondrial; Promotes the biosynthesis of heme as well as the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+). May be able to store large amounts of the metal in the form of a ferrihydrite mineral by oligomerization. Required for ecdysteroidogenesis in the prothoracic gland which is necessary for larval to pupal transition. Belongs to the frataxin family. | 0.990 |
| Fer3HCH | mfrn | FBpp0073576 | FBpp0084635 | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. | Mitoferrin; Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.663 |
