STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rtc1Probable RNA 3'-terminal phosphate cyclase-like protein; Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity); Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily. (384 aa)    
Predicted Functional Partners:
CG7728
LD38375p; GTP binding; U3 snoRNA binding; GTPase activity. It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA).
   
 0.999
bys
Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits; Belongs to the bystin family.
   
 
 0.998
l(2)k09022
HEAT repeat-containing protein 1 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity); Belongs to the HEATR1/UTP10 family.
   
 0.997
CG9799
LD47749p; It is involved in the biological process described with: rRNA processing.
   
 
 0.997
U3-55K
U3 small nuclear riboprotein factor 55K; RNA binding; snoRNA binding; U3 snoRNA binding. It is involved in the biological process described with: rRNA processing.
   
 
 0.997
l(3)72Dn
Lethal (3) 72Dn, isoform B; It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA).
   
 0.997
CG12325
LD10780p; It is involved in the biological process described with: ribosomal small subunit assembly; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA).
   
 
 0.997
CG30349
FI03455p.
   
 0.996
CG7246
RE67794p; snoRNA binding. It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA).
   
 
 0.995
CG4554
DRIM domain-containing protein.
   
 
 0.995
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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