Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CG11068AT20767p. (299 aa)    
Predicted Functional Partners:
CG6602
Uncharacterized protein.
      
 0.912
l(1)G0196
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]
      
 0.862
Ugt37C1
UDP-glycosyltransferase family 37 member C1; UDP-glycosyltransferase activity; transferase activity, transferring hexosyl groups. It is involved in the biological process described with: UDP-glucose metabolic process.
      
 0.827
CG43799
Uncharacterized protein.
      
 0.822
Cap-D2
Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
      
 0.780
CG2854
EG:BACH48C10.2 protein.
   
  
 0.774
RfC3
Replication factor C subunit 3; ATP binding; DNA clamp loader activity. It is involved in the biological process described with: leading strand elongation; DNA repair; sister chromatid cohesion; DNA-dependent DNA replication.
      
 0.743
dos
Protein daughter of sevenless; Essential component for signaling from various receptor tyrosine kinases such as Sevenless, TORSO and DER. Required for photoreceptor cell and wing development.
      
 0.742
Pino
Protein pinocchio; Plays a role in olfaction; Belongs to the pinocchio family.
      
 0.655
BBS5
Bardet-Biedl syndrome 5; Phosphatidylinositol-3-phosphate binding. It is involved in the biological process described with: cilium assembly; intracellular transport.
      
 0.654
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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