STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG33177IP20101p; Glutathione transferase activity; glutathione peroxidase activity. (167 aa)    
Predicted Functional Partners:
CG4558
Uncharacterized protein, isoform B.
      
 0.838
CG4306
RE30433p; Gamma-glutamylcyclotransferase activity.
      
 0.791
Ggt-1
Gamma-glutamyl transpeptidase (Ggt-1) encodes an enzyme that transfers the gamma-glutamyl moiety from donors to substrates, e.g. transfer to water generates glutamate. The roles of the product of Ggt-1 include glutathione metabolism, reproduction and light avoidance.
     
 0.789
GstS1
Glutathione S-transferase S1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May be involved in the detoxification of metabolites produced during cellular division and morphogenesis.
     
 0.772
GstT3
Glutathione S transferase T3 (GstT3) encodes an enzyme involved in glutathione metabolic processes; Belongs to the GST superfamily.
     
 0.768
PHGPx
PHGPx (PHGPx) encodes a peroxidase involved in intestinal stem cell homeostasis and the response to endoplasmic reticulum stress.
   
 
 0.766
CG15116
Peroxidase activity; glutathione peroxidase activity. It is involved in the biological process described with: oxidation-reduction process; multicellular organism reproduction; response to oxidative stress.
   
 
 0.738
GstT2
Glutathione S transferase T2 (GstT2) encodes an enzyme involved in glutathione metabolic processes; Belongs to the GST superfamily.
     
 0.734
GstT4
Glutathione peroxidase activity; glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process; Belongs to the GST superfamily.
     
 0.716
GstE4
Glutathione S transferase E4 (GstE4) encodes an enzyme involved in glutathione metabolic processes; Belongs to the GST superfamily.
   
 
 0.704
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.