STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG9514FI04917p; Flavin adenine dinucleotide binding; oxidoreductase activity; oxidoreductase activity, acting on CH-OH group of donors. It is involved in the biological process described with: oxidation-reduction process; ecdysteroid metabolic process; Belongs to the GMC oxidoreductase family. (726 aa)    
Predicted Functional Partners:
Aldh7A1
Aldehyde dehydrogenase 7 family member A1; Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. It is involved in the biological process described with: oxidation-reduction process.
 
 
 0.912
Pld3
GM01519p; Catalytic activity.
     
 0.880
Pisd
Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
     
 0.870
Pld
Phospholipase; Phosphatidylinositol binding; phospholipase D activity.
     
 0.858
CG33116
FI05338p; Phosphotransferase activity, for other substituted phosphate groups; ethanolaminephosphotransferase activity. It is involved in the biological process described with: phosphatidylethanolamine biosynthetic process; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.808
CG7149
GH11618p; Ethanolaminephosphotransferase activity; phosphotransferase activity, for other substituted phosphate groups. It is involved in the biological process described with: phosphatidylethanolamine biosynthetic process; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.807
CG3009
RH14732p; Calcium-dependent phospholipase A2 activity. It is involved in the biological process described with: arachidonic acid secretion; phospholipid metabolic process.
     
 0.800
nes
Lysophospholipid acyltransferase 5; Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (LPCAT activity). May also catalyze the conversion of lysophosphatidylethanolamine (1-acyl-2-hydroxy-sn-glycero-3- phosphoethanolamine or LPE) to phosphatidylethanolamine (1,2-diacyl-sn- glycero-3-phosphoethanolamine or PE) (LPEAT activity), as well as the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3- phospho-L-serine or LPS) to phosphatidylser [...]
     
  0.800
iPLA2-VIA
Calcium-independent phospholipase A2 VIA (iPLA2-VIA) encodes a protein that localizes to cytosol and mitochondria involved in repairing oxidized mitochondrial lipids, such as cardiolipin, and thus preventing cytochrome c release. It is partially responsible for cardiolipin depletion and monolysocardiolipin accumulation in Taz-deficient flies, which is a model of Barth syndrome.
     
  0.800
sPLA2
Secretory phospholipase A2, isoform A; Calcium-dependent phospholipase A2 activity. It is involved in the biological process described with: arachidonic acid secretion; phospholipid metabolic process.
     
 0.800
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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