STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cyp4s3Probable cytochrome P450 4s3; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. (495 aa)    
Predicted Functional Partners:
Cpr
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome p450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome b5 (By similarity). May function to clear the olfactory organ (antennae) from accumulating chemicals. In the N-terminal section; belongs to the flavodoxin family.
 
  
 
 0.909
CG13667
NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of the anamorsin/DRE2 homolog. Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family. In the N-terminal section; belongs to the flavodoxin family.
 
  
 
 0.900
CG14882
Uncharacterized protein, isoform A; [methionine synthase] reductase activity. It is involved in the biological process described with: oxidation-reduction process; methionine biosynthetic process.
 
  
 
 0.668
CG8814
LD25952p; fatty-acyl-CoA binding.
      
 0.604
CG7724
GH25466p; Oxidoreductase activity; 3-beta-hydroxy-delta5-steroid dehydrogenase activity; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; steroid delta-isomerase activity. It is involved in the biological process described with: oxidation-reduction process; steroid biosynthetic process; Belongs to the 3-beta-HSD family.
   
 
 0.578
Desi
Desiccate; PDZ domain binding; SH2 domain binding. It is involved in the biological process described with: sensory perception of taste; response to desiccation.
      
 0.532
CG9801
PP2C-like domain-containing protein CG9801; Catalytic activity.
      
 0.489
Pxd
Peroxidase (Pxd) encodes an enzyme that converts hydrogen peroxide to water and molecular oxygen, in the process oxidizing glutathione to glutathione disulfide. It is involved in the cellular response to oxidative stress; Belongs to the peroxidase family. XPO subfamily.
   
  
 0.477
Lip2
Lipase; Hydrolase activity, acting on ester bonds. It is involved in the biological process described with: lipid metabolic process; Belongs to the AB hydrolase superfamily. Lipase family.
   
 
 0.476
Ugt304A1
UDP-glycosyltransferase family 304 member A1; Transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity.
   
 
 0.470
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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