STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG6340GH25653p. (513 aa)    
Predicted Functional Partners:
ytr
Yantar, isoform A; Yantar (ytr) encodes a conserved arginine-rich protein involved in alternative splicing and hemocyte differentiation.
   
  
 0.844
CG4119
BcDNA.LD23634; mRNA binding. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome; mRNA splicing, via spliceosome.
   
  
 0.843
CG8675
CG8675-PA.
   
  
 0.840
CG10209
Uncharacterized protein, isoform B; CG10209 encodes a DNA binding nuclear apoptosis-inducing factor involved in the apoptotic process.
    
   0.692
CG9890
LD46465p; Nucleic acid binding.
    
 
 0.671
Ythdc1
YTH domain-containing protein 1; Regulator of alternative splicing that specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. Acts by acting as a reader of m6A methylation. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions.
   
    0.653
Caper
Caper, isoform A; Caper (Caper) encodes an RNA-binding protein involved in regulation of alternative mRNA splicing.
   
   0.608
CG10949
GH22016p; It is involved in the biological process described with: regulation of transcription by RNA polymerase II.
    
   0.553
CG1622
FI05227p; It is involved in the biological process described with: mRNA splicing, via spliceosome.
   
    0.526
eIF3d1
Eukaryotic translation initiation factor 3 subunit D-1; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs.
      
 0.489
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.