node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ca-P60A | Cam | FBpp0072125 | FBpp0293502 | Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type; Sarco/endoplasmic reticulum Ca(2+)-ATPase is an endoplasmic reticulum (ER) calcium pump with roles in ER calcium homeostasis and lipid storage | Calmodulin, isoform c; Calmodulin is a Calcium-binding messenger protein. It acts as a part of the calcium signal transduction pathway and interacts with various target proteins such as kinases or phosphatases. It is involved in actin filament-based movement, mitotic spinde assembly, axon guidance, DNA damage response, autophagy, cell death, sensory perception, and muscle homeostasis | 0.808 |
Ca-P60A | Itp-r83A | FBpp0072125 | FBpp0078336 | Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type; Sarco/endoplasmic reticulum Ca(2+)-ATPase is an endoplasmic reticulum (ER) calcium pump with roles in ER calcium homeostasis and lipid storage | Inositol 1,4,5,-trisphosphate receptor, isoform b; Inositol 1,4,5,-tris-phosphate receptor (Itp-r83A) is an intracellular ligand gated calcium channel. It functions downstream of G-protein coupled receptors that activate Gq/PLCbeta signaling and generate inositol tris-phosphate. Itp-r83A depletion affects ecdysone release, response to nutritional stress, lipid metabolism and flight | 0.981 |
Ca-P60A | NFAT | FBpp0072125 | FBpp0111893 | Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type; Sarco/endoplasmic reticulum Ca(2+)-ATPase is an endoplasmic reticulum (ER) calcium pump with roles in ER calcium homeostasis and lipid storage | NFAT nuclear factor, isoform B; Sequence-specific DNA binding transcription factor activity. It is involved in the biological process described with: regulation of response to DNA damage stimulus; negative regulation of Ras protein signal transduction; negative regulation of synaptic vesicle exocytosis; imaginal disc-derived wing morphogenesis; transcription, DNA-templated; regulation of transcription, DNA-templated; response to salt stress | 0.741 |
Ca-P60A | RyR | FBpp0072125 | FBpp0293114 | Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type; Sarco/endoplasmic reticulum Ca(2+)-ATPase is an endoplasmic reticulum (ER) calcium pump with roles in ER calcium homeostasis and lipid storage | Ryanodine receptor; Intracellular calcium channel that is required for proper muscle function during embryonic development and may be essential for excitation-contraction coupling in larval body wall muscles; Belongs to the ryanodine receptor (TC 1.A.3.1) family | 0.989 |
Ca-P60A | Stim | FBpp0072125 | FBpp0073955 | Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type; Sarco/endoplasmic reticulum Ca(2+)-ATPase is an endoplasmic reticulum (ER) calcium pump with roles in ER calcium homeostasis and lipid storage | Stromal interaction molecule, isoform a; Stromal interaction molecule homolog; Plays a role in mediating Ca(2+) influx following depletion of intracellular Ca(2+) stores | 0.980 |
Ca-P60A | Tm2 | FBpp0072125 | FBpp0082535 | Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type; Sarco/endoplasmic reticulum Ca(2+)-ATPase is an endoplasmic reticulum (ER) calcium pump with roles in ER calcium homeostasis and lipid storage | Tropomyosin 2, isoform f; Tropomyosin-2; Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction. May also regulate motor systems required to maintain nuclear integrity and apico-basal polarity during embryogenesis | 0.736 |
Ca-P60A | olf186-F | FBpp0072125 | FBpp0113106 | Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type; Sarco/endoplasmic reticulum Ca(2+)-ATPase is an endoplasmic reticulum (ER) calcium pump with roles in ER calcium homeostasis and lipid storage | Calcium release-activated calcium channel protein 1; Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores. Regulates transcription factor NFAT nuclear import | 0.944 |
Ca-P60A | trp | FBpp0072125 | FBpp0084879 | Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type; Sarco/endoplasmic reticulum Ca(2+)-ATPase is an endoplasmic reticulum (ER) calcium pump with roles in ER calcium homeostasis and lipid storage | Transient receptor potential protein; A light-sensitive calcium channel that is required for inositide-mediated Ca(2+) entry in the retina during phospholipase C (PLC)-mediated phototransduction. Ca(2+) influx may then feed back and inhibit PLC, thereby facilitating phosphatidylinositol 4,5 bisphosphate (PIP2) recycling. Trp and trpl act together in the light response, though it is unclear whether as heteromultimers or as distinct units, and are activated by fatty acids and metabolic stress. Also required for olfactory adaptation and may be involved in olfactory system development; Bel [...] | 0.774 |
Cam | Ca-P60A | FBpp0293502 | FBpp0072125 | Calmodulin, isoform c; Calmodulin is a Calcium-binding messenger protein. It acts as a part of the calcium signal transduction pathway and interacts with various target proteins such as kinases or phosphatases. It is involved in actin filament-based movement, mitotic spinde assembly, axon guidance, DNA damage response, autophagy, cell death, sensory perception, and muscle homeostasis | Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type; Sarco/endoplasmic reticulum Ca(2+)-ATPase is an endoplasmic reticulum (ER) calcium pump with roles in ER calcium homeostasis and lipid storage | 0.808 |
Cam | Itp-r83A | FBpp0293502 | FBpp0078336 | Calmodulin, isoform c; Calmodulin is a Calcium-binding messenger protein. It acts as a part of the calcium signal transduction pathway and interacts with various target proteins such as kinases or phosphatases. It is involved in actin filament-based movement, mitotic spinde assembly, axon guidance, DNA damage response, autophagy, cell death, sensory perception, and muscle homeostasis | Inositol 1,4,5,-trisphosphate receptor, isoform b; Inositol 1,4,5,-tris-phosphate receptor (Itp-r83A) is an intracellular ligand gated calcium channel. It functions downstream of G-protein coupled receptors that activate Gq/PLCbeta signaling and generate inositol tris-phosphate. Itp-r83A depletion affects ecdysone release, response to nutritional stress, lipid metabolism and flight | 0.934 |
Cam | NFAT | FBpp0293502 | FBpp0111893 | Calmodulin, isoform c; Calmodulin is a Calcium-binding messenger protein. It acts as a part of the calcium signal transduction pathway and interacts with various target proteins such as kinases or phosphatases. It is involved in actin filament-based movement, mitotic spinde assembly, axon guidance, DNA damage response, autophagy, cell death, sensory perception, and muscle homeostasis | NFAT nuclear factor, isoform B; Sequence-specific DNA binding transcription factor activity. It is involved in the biological process described with: regulation of response to DNA damage stimulus; negative regulation of Ras protein signal transduction; negative regulation of synaptic vesicle exocytosis; imaginal disc-derived wing morphogenesis; transcription, DNA-templated; regulation of transcription, DNA-templated; response to salt stress | 0.906 |
Cam | RyR | FBpp0293502 | FBpp0293114 | Calmodulin, isoform c; Calmodulin is a Calcium-binding messenger protein. It acts as a part of the calcium signal transduction pathway and interacts with various target proteins such as kinases or phosphatases. It is involved in actin filament-based movement, mitotic spinde assembly, axon guidance, DNA damage response, autophagy, cell death, sensory perception, and muscle homeostasis | Ryanodine receptor; Intracellular calcium channel that is required for proper muscle function during embryonic development and may be essential for excitation-contraction coupling in larval body wall muscles; Belongs to the ryanodine receptor (TC 1.A.3.1) family | 0.951 |
Cam | Stim | FBpp0293502 | FBpp0073955 | Calmodulin, isoform c; Calmodulin is a Calcium-binding messenger protein. It acts as a part of the calcium signal transduction pathway and interacts with various target proteins such as kinases or phosphatases. It is involved in actin filament-based movement, mitotic spinde assembly, axon guidance, DNA damage response, autophagy, cell death, sensory perception, and muscle homeostasis | Stromal interaction molecule, isoform a; Stromal interaction molecule homolog; Plays a role in mediating Ca(2+) influx following depletion of intracellular Ca(2+) stores | 0.951 |
Cam | Tm2 | FBpp0293502 | FBpp0082535 | Calmodulin, isoform c; Calmodulin is a Calcium-binding messenger protein. It acts as a part of the calcium signal transduction pathway and interacts with various target proteins such as kinases or phosphatases. It is involved in actin filament-based movement, mitotic spinde assembly, axon guidance, DNA damage response, autophagy, cell death, sensory perception, and muscle homeostasis | Tropomyosin 2, isoform f; Tropomyosin-2; Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction. May also regulate motor systems required to maintain nuclear integrity and apico-basal polarity during embryogenesis | 0.635 |
Cam | olf186-F | FBpp0293502 | FBpp0113106 | Calmodulin, isoform c; Calmodulin is a Calcium-binding messenger protein. It acts as a part of the calcium signal transduction pathway and interacts with various target proteins such as kinases or phosphatases. It is involved in actin filament-based movement, mitotic spinde assembly, axon guidance, DNA damage response, autophagy, cell death, sensory perception, and muscle homeostasis | Calcium release-activated calcium channel protein 1; Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores. Regulates transcription factor NFAT nuclear import | 0.717 |
Cam | trp | FBpp0293502 | FBpp0084879 | Calmodulin, isoform c; Calmodulin is a Calcium-binding messenger protein. It acts as a part of the calcium signal transduction pathway and interacts with various target proteins such as kinases or phosphatases. It is involved in actin filament-based movement, mitotic spinde assembly, axon guidance, DNA damage response, autophagy, cell death, sensory perception, and muscle homeostasis | Transient receptor potential protein; A light-sensitive calcium channel that is required for inositide-mediated Ca(2+) entry in the retina during phospholipase C (PLC)-mediated phototransduction. Ca(2+) influx may then feed back and inhibit PLC, thereby facilitating phosphatidylinositol 4,5 bisphosphate (PIP2) recycling. Trp and trpl act together in the light response, though it is unclear whether as heteromultimers or as distinct units, and are activated by fatty acids and metabolic stress. Also required for olfactory adaptation and may be involved in olfactory system development; Bel [...] | 0.940 |
Itp-r83A | Ca-P60A | FBpp0078336 | FBpp0072125 | Inositol 1,4,5,-trisphosphate receptor, isoform b; Inositol 1,4,5,-tris-phosphate receptor (Itp-r83A) is an intracellular ligand gated calcium channel. It functions downstream of G-protein coupled receptors that activate Gq/PLCbeta signaling and generate inositol tris-phosphate. Itp-r83A depletion affects ecdysone release, response to nutritional stress, lipid metabolism and flight | Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type; Sarco/endoplasmic reticulum Ca(2+)-ATPase is an endoplasmic reticulum (ER) calcium pump with roles in ER calcium homeostasis and lipid storage | 0.981 |
Itp-r83A | Cam | FBpp0078336 | FBpp0293502 | Inositol 1,4,5,-trisphosphate receptor, isoform b; Inositol 1,4,5,-tris-phosphate receptor (Itp-r83A) is an intracellular ligand gated calcium channel. It functions downstream of G-protein coupled receptors that activate Gq/PLCbeta signaling and generate inositol tris-phosphate. Itp-r83A depletion affects ecdysone release, response to nutritional stress, lipid metabolism and flight | Calmodulin, isoform c; Calmodulin is a Calcium-binding messenger protein. It acts as a part of the calcium signal transduction pathway and interacts with various target proteins such as kinases or phosphatases. It is involved in actin filament-based movement, mitotic spinde assembly, axon guidance, DNA damage response, autophagy, cell death, sensory perception, and muscle homeostasis | 0.934 |
Itp-r83A | NFAT | FBpp0078336 | FBpp0111893 | Inositol 1,4,5,-trisphosphate receptor, isoform b; Inositol 1,4,5,-tris-phosphate receptor (Itp-r83A) is an intracellular ligand gated calcium channel. It functions downstream of G-protein coupled receptors that activate Gq/PLCbeta signaling and generate inositol tris-phosphate. Itp-r83A depletion affects ecdysone release, response to nutritional stress, lipid metabolism and flight | NFAT nuclear factor, isoform B; Sequence-specific DNA binding transcription factor activity. It is involved in the biological process described with: regulation of response to DNA damage stimulus; negative regulation of Ras protein signal transduction; negative regulation of synaptic vesicle exocytosis; imaginal disc-derived wing morphogenesis; transcription, DNA-templated; regulation of transcription, DNA-templated; response to salt stress | 0.663 |
Itp-r83A | RyR | FBpp0078336 | FBpp0293114 | Inositol 1,4,5,-trisphosphate receptor, isoform b; Inositol 1,4,5,-tris-phosphate receptor (Itp-r83A) is an intracellular ligand gated calcium channel. It functions downstream of G-protein coupled receptors that activate Gq/PLCbeta signaling and generate inositol tris-phosphate. Itp-r83A depletion affects ecdysone release, response to nutritional stress, lipid metabolism and flight | Ryanodine receptor; Intracellular calcium channel that is required for proper muscle function during embryonic development and may be essential for excitation-contraction coupling in larval body wall muscles; Belongs to the ryanodine receptor (TC 1.A.3.1) family | 0.564 |