STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG4239GH25683p; Cation channel activity. It is involved in the biological process described with: monovalent inorganic cation transport. (276 aa)    
Predicted Functional Partners:
Tret1-2
Facilitated trehalose transporter Tret1-2 homolog; Fails to transport trehalose; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.
      
 0.621
Fcp3C
Follicle cell protein 3C-1.
      
 0.610
regucalcin
Regucalcin, isoform D; Calcium ion binding; gluconolactonase activity. It is involved in the biological process described with: L-ascorbic acid biosynthetic process; multicellular organism reproduction.
   
  
 0.533
Tsp47F
Tetraspanin 47F (Tsp47F) encodes a member of the tetraspanin superfamily of integral membrane proteins that are involved in cell adhesion and signal transduction.
      
 0.523
Tret1-1
Facilitated trehalose transporter Tret1-1; Low-capacity facilitative transporter for trehalose. Does not transport maltose, sucrose or lactose. Mediates the bidirectional transfer of trehalose. Responsible for the transport of trehalose synthesized in the fat body and the incorporation of trehalose into other tissues that require a carbon source, thereby regulating trehalose levels in the hemolymph; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.
      
 0.515
Wsck
Putative tyrosine-protein kinase Wsck; Putative receptor with tyrosine-protein kinase activity.
      
 0.465
trol
Terribly reduced optic lobes (trol) encodes the extracellular matrix component Perlecan, a secreted heparan sulfate proteoglycan. It regulates cell-signaling by multiple growth factors including those in the hedgehog, wingless/WNT, FGF, TGFbeta, EGF, and VEGF families, thus playing a role in many developmental patterning decisions.
   
  
 0.455
Ykt6
YKT6 v-SNARE; Protein-cysteine S-palmitoyltransferase activity; SNAP receptor activity. It is involved in the biological process described with: endoplasmic reticulum to Golgi vesicle-mediated transport; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; vesicle-mediated transport; Belongs to the synaptobrevin family.
 
      0.451
CG8180
Uncharacterized protein, isoform B.
      
 0.436
Sema2a
Semaphorin-2A; Semaphorin 2a (Sema2a) encodes a secreted member of the semaphorin protein family. It utilizes the receptor encoded by PlexB to mediate both repulsive and attractive axon guidance. It also utilizes the transmembrane semaphorin encoded by Sema1a as a receptor for dendrite process guidance.
  
   
 0.427
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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