Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDC50CDC50, isoform A; It is involved in the biological process described with: phospholipid transport; Belongs to the CDC50/LEM3 family. (357 aa)    
Predicted Functional Partners:
ATP8A
ATP binding; magnesium ion binding; ATPase-coupled intramembrane lipid transporter activity. It is involved in the biological process described with: phospholipid translocation; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
    
 0.996
CG4301
ATPase-coupled intramembrane lipid transporter activity; ATP binding; magnesium ion binding. It is involved in the biological process described with: phospholipid translocation; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
   
 0.976
CG9981
ATPase-coupled intramembrane lipid transporter activity; magnesium ion binding; ATP binding. It is involved in the biological process described with: phospholipid translocation; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
    
 0.976
CG34430
RT07360p; Belongs to the BI1 family.
   
  
 0.745
CG2875
LD21615p; It is involved in the biological process described with: ribosome biogenesis.
   
  
 0.741
ATP8B
ATPase 8B (ATP8B) encodes a phospholipid flippase involved in olfaction; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
    
 
 0.721
CG17249
LD14179p; It is involved in the biological process described with: mitotic cell cycle checkpoint.
      
 0.689
Pngl
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins [...]
   
   0.687
CG33298
Magnesium ion binding; ATP binding; ATPase-coupled intramembrane lipid transporter activity. It is involved in the biological process described with: phospholipid translocation; Golgi organization; intracellular protein transport; response to endoplasmic reticulum stress; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
    
 
 0.679
CG13016
FI21814p1.
   
  
 0.664
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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