node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGO2 | Taf11 | FBpp0075313 | FBpp0079514 | Protein argonaute-2; Essential for RNA interference (RNAi); double-stranded RNA induces potent and specific gene silencing. RNAi is mediated by the RNA-induced silencing complex (RISC), a sequence-specific, multicomponent nuclease that destroys or silences messenger RNAs homologous to the silencing trigger; Belongs to the argonaute family. Ago subfamily. | TBP-associated factor 11 (Taf11) encodes a protein that forms part of the multisubunit basal transcription factor TFIID. It enhances RNA interference efficiency, organizing the assembly of the RISC loading complex. | 0.936 |
AGO2 | mldr | FBpp0075313 | FBpp0293947 | Protein argonaute-2; Essential for RNA interference (RNAi); double-stranded RNA induces potent and specific gene silencing. RNAi is mediated by the RNA-induced silencing complex (RISC), a sequence-specific, multicomponent nuclease that destroys or silences messenger RNAs homologous to the silencing trigger; Belongs to the argonaute family. Ago subfamily. | Mulder, isoform A; Mulder (mldr) encodes a protein involved in mitochondrial tRNA processing. | 0.900 |
AGO2 | pasha | FBpp0075313 | FBpp0085181 | Protein argonaute-2; Essential for RNA interference (RNAi); double-stranded RNA induces potent and specific gene silencing. RNAi is mediated by the RNA-induced silencing complex (RISC), a sequence-specific, multicomponent nuclease that destroys or silences messenger RNAs homologous to the silencing trigger; Belongs to the argonaute family. Ago subfamily. | Partner of drosha (pasha) encodes a protein involved in oogenesis and miRNA processing. | 0.936 |
AGO2 | r2d2 | FBpp0075313 | FBpp0079112 | Protein argonaute-2; Essential for RNA interference (RNAi); double-stranded RNA induces potent and specific gene silencing. RNAi is mediated by the RNA-induced silencing complex (RISC), a sequence-specific, multicomponent nuclease that destroys or silences messenger RNAs homologous to the silencing trigger; Belongs to the argonaute family. Ago subfamily. | R2d2, isoform A; R2d2 (r2d2) encodes a double-stranded RNA-binding protein. It interacts with the product of Dcr-2 to form the core of RISC loading complex, which recruits duplex siRNA to the RISC. | 0.988 |
AGO2 | rswl | FBpp0075313 | FBpp0085875 | Protein argonaute-2; Essential for RNA interference (RNAi); double-stranded RNA induces potent and specific gene silencing. RNAi is mediated by the RNA-induced silencing complex (RISC), a sequence-specific, multicomponent nuclease that destroys or silences messenger RNAs homologous to the silencing trigger; Belongs to the argonaute family. Ago subfamily. | Mitochondrial ribonuclease P protein 1 homolog; May function in mitochondrial tRNA maturation; Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family. | 0.900 |
AGO2 | scu | FBpp0075313 | FBpp0074285 | Protein argonaute-2; Essential for RNA interference (RNAi); double-stranded RNA induces potent and specific gene silencing. RNAi is mediated by the RNA-induced silencing complex (RISC), a sequence-specific, multicomponent nuclease that destroys or silences messenger RNAs homologous to the silencing trigger; Belongs to the argonaute family. Ago subfamily. | 3-hydroxyacyl-CoA dehydrogenase type-2; May function in mitochondrial tRNA maturation. Catalyzes the beta-oxidation at position 17 of androgens and estrogens, and has 3- alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-beta-hydroxylated bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. Required for cell survival during embryonic development. May play a role in germline formation; Belongs to the short-chain dehydrogenases/reductases [...] | 0.900 |
Echs1 | Mtpalpha | FBpp0086770 | FBpp0079454 | Enoyl-CoA hydratase, short chain 1, isoform A; enoyl-CoA hydratase activity. It is involved in the biological process described with: fatty acid beta-oxidation; Belongs to the enoyl-CoA hydratase/isomerase family. | Mitochondrial trifunctional protein alpha subunit (Mtpalpha) encodes a subunit of the mitochondrial trifunctional protein. It possesses 3-enoyl-CoA hydratase and 3-hydroxyacyl-CoA dehydrogenase activities, which catalyze the second and third steps,respectively, of the beta-oxidation of long-chain fatty acids. | 0.950 |
Echs1 | Mtpbeta | FBpp0086770 | FBpp0072135 | Enoyl-CoA hydratase, short chain 1, isoform A; enoyl-CoA hydratase activity. It is involved in the biological process described with: fatty acid beta-oxidation; Belongs to the enoyl-CoA hydratase/isomerase family. | GH13256p; Mitochondrial trifunctional protein beta subunit (Mtpbeta) encodes a protein involved in fatty acid beta-oxidation; Belongs to the thiolase-like superfamily. Thiolase family. | 0.965 |
Echs1 | scu | FBpp0086770 | FBpp0074285 | Enoyl-CoA hydratase, short chain 1, isoform A; enoyl-CoA hydratase activity. It is involved in the biological process described with: fatty acid beta-oxidation; Belongs to the enoyl-CoA hydratase/isomerase family. | 3-hydroxyacyl-CoA dehydrogenase type-2; May function in mitochondrial tRNA maturation. Catalyzes the beta-oxidation at position 17 of androgens and estrogens, and has 3- alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-beta-hydroxylated bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. Required for cell survival during embryonic development. May play a role in germline formation; Belongs to the short-chain dehydrogenases/reductases [...] | 0.989 |
Echs1 | yip2 | FBpp0086770 | FBpp0079472 | Enoyl-CoA hydratase, short chain 1, isoform A; enoyl-CoA hydratase activity. It is involved in the biological process described with: fatty acid beta-oxidation; Belongs to the enoyl-CoA hydratase/isomerase family. | Yippee interacting protein 2; acetyl-CoA C-acyltransferase activity; acetyl-CoA C-acetyltransferase activity. It is involved in the biological process described with: fatty acid beta-oxidation; Belongs to the thiolase-like superfamily. Thiolase family. | 0.868 |
Mtpalpha | Echs1 | FBpp0079454 | FBpp0086770 | Mitochondrial trifunctional protein alpha subunit (Mtpalpha) encodes a subunit of the mitochondrial trifunctional protein. It possesses 3-enoyl-CoA hydratase and 3-hydroxyacyl-CoA dehydrogenase activities, which catalyze the second and third steps,respectively, of the beta-oxidation of long-chain fatty acids. | Enoyl-CoA hydratase, short chain 1, isoform A; enoyl-CoA hydratase activity. It is involved in the biological process described with: fatty acid beta-oxidation; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.950 |
Mtpalpha | Mtpbeta | FBpp0079454 | FBpp0072135 | Mitochondrial trifunctional protein alpha subunit (Mtpalpha) encodes a subunit of the mitochondrial trifunctional protein. It possesses 3-enoyl-CoA hydratase and 3-hydroxyacyl-CoA dehydrogenase activities, which catalyze the second and third steps,respectively, of the beta-oxidation of long-chain fatty acids. | GH13256p; Mitochondrial trifunctional protein beta subunit (Mtpbeta) encodes a protein involved in fatty acid beta-oxidation; Belongs to the thiolase-like superfamily. Thiolase family. | 0.999 |
Mtpalpha | scu | FBpp0079454 | FBpp0074285 | Mitochondrial trifunctional protein alpha subunit (Mtpalpha) encodes a subunit of the mitochondrial trifunctional protein. It possesses 3-enoyl-CoA hydratase and 3-hydroxyacyl-CoA dehydrogenase activities, which catalyze the second and third steps,respectively, of the beta-oxidation of long-chain fatty acids. | 3-hydroxyacyl-CoA dehydrogenase type-2; May function in mitochondrial tRNA maturation. Catalyzes the beta-oxidation at position 17 of androgens and estrogens, and has 3- alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-beta-hydroxylated bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. Required for cell survival during embryonic development. May play a role in germline formation; Belongs to the short-chain dehydrogenases/reductases [...] | 0.942 |
Mtpalpha | yip2 | FBpp0079454 | FBpp0079472 | Mitochondrial trifunctional protein alpha subunit (Mtpalpha) encodes a subunit of the mitochondrial trifunctional protein. It possesses 3-enoyl-CoA hydratase and 3-hydroxyacyl-CoA dehydrogenase activities, which catalyze the second and third steps,respectively, of the beta-oxidation of long-chain fatty acids. | Yippee interacting protein 2; acetyl-CoA C-acyltransferase activity; acetyl-CoA C-acetyltransferase activity. It is involved in the biological process described with: fatty acid beta-oxidation; Belongs to the thiolase-like superfamily. Thiolase family. | 0.996 |
Mtpbeta | Echs1 | FBpp0072135 | FBpp0086770 | GH13256p; Mitochondrial trifunctional protein beta subunit (Mtpbeta) encodes a protein involved in fatty acid beta-oxidation; Belongs to the thiolase-like superfamily. Thiolase family. | Enoyl-CoA hydratase, short chain 1, isoform A; enoyl-CoA hydratase activity. It is involved in the biological process described with: fatty acid beta-oxidation; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.965 |
Mtpbeta | Mtpalpha | FBpp0072135 | FBpp0079454 | GH13256p; Mitochondrial trifunctional protein beta subunit (Mtpbeta) encodes a protein involved in fatty acid beta-oxidation; Belongs to the thiolase-like superfamily. Thiolase family. | Mitochondrial trifunctional protein alpha subunit (Mtpalpha) encodes a subunit of the mitochondrial trifunctional protein. It possesses 3-enoyl-CoA hydratase and 3-hydroxyacyl-CoA dehydrogenase activities, which catalyze the second and third steps,respectively, of the beta-oxidation of long-chain fatty acids. | 0.999 |
Mtpbeta | scu | FBpp0072135 | FBpp0074285 | GH13256p; Mitochondrial trifunctional protein beta subunit (Mtpbeta) encodes a protein involved in fatty acid beta-oxidation; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxyacyl-CoA dehydrogenase type-2; May function in mitochondrial tRNA maturation. Catalyzes the beta-oxidation at position 17 of androgens and estrogens, and has 3- alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-beta-hydroxylated bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. Required for cell survival during embryonic development. May play a role in germline formation; Belongs to the short-chain dehydrogenases/reductases [...] | 0.964 |
Mtpbeta | yip2 | FBpp0072135 | FBpp0079472 | GH13256p; Mitochondrial trifunctional protein beta subunit (Mtpbeta) encodes a protein involved in fatty acid beta-oxidation; Belongs to the thiolase-like superfamily. Thiolase family. | Yippee interacting protein 2; acetyl-CoA C-acyltransferase activity; acetyl-CoA C-acetyltransferase activity. It is involved in the biological process described with: fatty acid beta-oxidation; Belongs to the thiolase-like superfamily. Thiolase family. | 0.970 |
Taf11 | AGO2 | FBpp0079514 | FBpp0075313 | TBP-associated factor 11 (Taf11) encodes a protein that forms part of the multisubunit basal transcription factor TFIID. It enhances RNA interference efficiency, organizing the assembly of the RISC loading complex. | Protein argonaute-2; Essential for RNA interference (RNAi); double-stranded RNA induces potent and specific gene silencing. RNAi is mediated by the RNA-induced silencing complex (RISC), a sequence-specific, multicomponent nuclease that destroys or silences messenger RNAs homologous to the silencing trigger; Belongs to the argonaute family. Ago subfamily. | 0.936 |
Taf11 | mldr | FBpp0079514 | FBpp0293947 | TBP-associated factor 11 (Taf11) encodes a protein that forms part of the multisubunit basal transcription factor TFIID. It enhances RNA interference efficiency, organizing the assembly of the RISC loading complex. | Mulder, isoform A; Mulder (mldr) encodes a protein involved in mitochondrial tRNA processing. | 0.901 |