node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG15443 | CG6179 | FBpp0307133 | FBpp0074330 | RH51096p. | Nitric oxide synthase-interacting protein homolog; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. | 0.597 |
CG32850 | CG6179 | FBpp0088192 | FBpp0074330 | GEO07743p1; Zinc ion binding; ubiquitin-protein transferase activity; ubiquitin protein ligase activity. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; protein autoubiquitination. | Nitric oxide synthase-interacting protein homolog; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. | 0.608 |
CG32850 | Mkrn1 | FBpp0088192 | FBpp0078038 | GEO07743p1; Zinc ion binding; ubiquitin-protein transferase activity; ubiquitin protein ligase activity. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; protein autoubiquitination. | Makorin 1, isoform A; Ubiquitin protein ligase activity; metal ion binding; ubiquitin-protein transferase activity; zinc ion binding. It is involved in the biological process described with: protein polyubiquitination; positive regulation of insulin receptor signaling pathway; positive regulation of oogenesis. | 0.410 |
CG32850 | Pex2 | FBpp0088192 | FBpp0076329 | GEO07743p1; Zinc ion binding; ubiquitin-protein transferase activity; ubiquitin protein ligase activity. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; protein autoubiquitination. | Peroxin 2 (Pex2) encodes a peroxisome protein important for sperm development. | 0.430 |
CG3436 | CG6179 | FBpp0309501 | FBpp0074330 | GM13767p; RNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome; mitotic cell cycle. | Nitric oxide synthase-interacting protein homolog; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. | 0.901 |
CG6179 | CG15443 | FBpp0074330 | FBpp0307133 | Nitric oxide synthase-interacting protein homolog; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. | RH51096p. | 0.597 |
CG6179 | CG32850 | FBpp0074330 | FBpp0088192 | Nitric oxide synthase-interacting protein homolog; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. | GEO07743p1; Zinc ion binding; ubiquitin-protein transferase activity; ubiquitin protein ligase activity. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; protein autoubiquitination. | 0.608 |
CG6179 | CG3436 | FBpp0074330 | FBpp0309501 | Nitric oxide synthase-interacting protein homolog; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. | GM13767p; RNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome; mitotic cell cycle. | 0.901 |
CG6179 | CG7718 | FBpp0074330 | FBpp0083097 | Nitric oxide synthase-interacting protein homolog; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. | 0.613 |
CG6179 | CG7974 | FBpp0074330 | FBpp0306051 | Nitric oxide synthase-interacting protein homolog; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. | GM02612p; It is involved in the biological process described with: regulation of mRNA splicing, via spliceosome. | 0.615 |
CG6179 | Mkrn1 | FBpp0074330 | FBpp0078038 | Nitric oxide synthase-interacting protein homolog; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. | Makorin 1, isoform A; Ubiquitin protein ligase activity; metal ion binding; ubiquitin-protein transferase activity; zinc ion binding. It is involved in the biological process described with: protein polyubiquitination; positive regulation of insulin receptor signaling pathway; positive regulation of oogenesis. | 0.542 |
CG6179 | Nos | FBpp0074330 | FBpp0079777 | Nitric oxide synthase-interacting protein homolog; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. | Nitric oxide synthase; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. Truncated isoforms (isoform 3- isoform 6) are able to form intracellular complexes with the full- length protein and serve as dominant negative inhibitors of the enzyme activity; Belongs to the NOS family. | 0.813 |
CG6179 | Pex12 | FBpp0074330 | FBpp0305188 | Nitric oxide synthase-interacting protein homolog; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. | Peroxin 12 (Pex12) encodes a peroxisome protein important for sperm development; Belongs to the pex2/pex10/pex12 family. | 0.493 |
CG6179 | Pex2 | FBpp0074330 | FBpp0076329 | Nitric oxide synthase-interacting protein homolog; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. | Peroxin 2 (Pex2) encodes a peroxisome protein important for sperm development. | 0.603 |
CG6179 | Unc-89 | FBpp0074330 | FBpp0112375 | Nitric oxide synthase-interacting protein homolog; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. | Obscurin; Structural component of the muscle M line which is involved in assembly and organization of sarcomere. Required for the development and organization of indirect flight muscle sarcomeres by regulating the formation of M line and H zone and the correct assembly of thick and thin filaments in the sarcomere. Likely to have serine/threonine-protein kinase activity as one of the two protein kinase domains appears to be functional (Probable). | 0.500 |
CG7718 | CG6179 | FBpp0083097 | FBpp0074330 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. | Nitric oxide synthase-interacting protein homolog; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. | 0.613 |
CG7974 | CG6179 | FBpp0306051 | FBpp0074330 | GM02612p; It is involved in the biological process described with: regulation of mRNA splicing, via spliceosome. | Nitric oxide synthase-interacting protein homolog; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. | 0.615 |
Mkrn1 | CG32850 | FBpp0078038 | FBpp0088192 | Makorin 1, isoform A; Ubiquitin protein ligase activity; metal ion binding; ubiquitin-protein transferase activity; zinc ion binding. It is involved in the biological process described with: protein polyubiquitination; positive regulation of insulin receptor signaling pathway; positive regulation of oogenesis. | GEO07743p1; Zinc ion binding; ubiquitin-protein transferase activity; ubiquitin protein ligase activity. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; protein autoubiquitination. | 0.410 |
Mkrn1 | CG6179 | FBpp0078038 | FBpp0074330 | Makorin 1, isoform A; Ubiquitin protein ligase activity; metal ion binding; ubiquitin-protein transferase activity; zinc ion binding. It is involved in the biological process described with: protein polyubiquitination; positive regulation of insulin receptor signaling pathway; positive regulation of oogenesis. | Nitric oxide synthase-interacting protein homolog; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. | 0.542 |
Nos | CG6179 | FBpp0079777 | FBpp0074330 | Nitric oxide synthase; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. Truncated isoforms (isoform 3- isoform 6) are able to form intracellular complexes with the full- length protein and serve as dominant negative inhibitors of the enzyme activity; Belongs to the NOS family. | Nitric oxide synthase-interacting protein homolog; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. | 0.813 |