STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG7914FAD-binding FR-type domain-containing protein; Oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. (315 aa)    
Predicted Functional Partners:
Dhod
Dihydroorotate dehydrogenase (Dhod) encodes a protein that is associated with the inner mitochondrial membrane. It catalyzes the fourth step of de novo pyrimidine biosynthesis, which is required for normal cuticle formation and oogenesis.
  
 
 0.964
CG11257
FI21247p1; Cytochrome-b5 reductase activity, acting on NAD(P)H; heme binding. It is involved in the biological process described with: oxidation-reduction process; superoxide metabolic process; generation of precursor metabolites and energy.
   
 0.953
su(r)
Suppressor of rudimentary (su(r)) encodes a dihydropyrimidine dehydrogenase, the first step of pyrimidine catabolism. su(r) depletion does not produce visible phenotypes, but synergistic effects are exhibited by combining mutants with genes affecting pyrimidine biosynthesis and beta-alanine metabolism.
  
 
 0.937
r
Glutamine-dependent carbamoyl-phosphate synthase; Rudimentary (r) encodes the CAD protein that catalyzes the initial steps of de novo pyrimidine biosynthesis. r depletion results in wing malformations and pyrimidine auxotrophy.
  
  
 0.915
CG5946
FAD binding; cytochrome-b5 reductase activity, acting on NAD(P)H. It is involved in the biological process described with: retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; regulation of lipid storage; oxidation-reduction process; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
     
 
0.900
Cyt-b5
Cytochrome b5; Cytochrome b5 is a membrane-bound hemoprotein which functions as an electron carrier for several membrane-bound oxygenases.
   
 
 0.893
CG32576
Uncharacterized protein, isoform B; It is involved in the biological process described with: vesicle-mediated transport.
  
  
 0.892
CG32816
FI17329p1.
  
  
 0.825
r-l
Orotidine 5'-phosphate decarboxylase; Rudimentary-like (r-l) encodes an enzyme involved in the novo pyrimidine biosynthesis; In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
  
 0.820
CG3566
Uncharacterized protein, isoform B; Heme binding; electron transfer activity; Belongs to the cytochrome b5 family.
   
 
 0.797
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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